Oasys and Occupational Asthma

This website contains information on Occupational Asthma and a free multi award winning computer program called OASYS, which is used to help diagnose Occupational Asthma from serial peak flow records. Oasys shows further information and downloads for the Oasys program. References is a searchable database of more than 5000 published papers in the field of occupational asthma. Causes shows some of the causes of occupational asthma. The Shield scheme reports some statistics for occupational asthma, mainly in the West midlands region, UK. BOHRF shows the evidence based occupational asthma guidelines for the UK. The interactive Case Histories are a learning resource for interested health professionals. There are also Medics, Specialists, Employers and Worker sections.

Latest News

Occupational asthma: Changes in NSBR and FeNO in 29% of workers with a positive SIC to epoxy resins Changes in NSBR and FeNO in 29% of workers with a positive SIC to epoxy resins 27 01 2021
Occupational asthma: Pre-employment NSBR unhelpful in predicting potroom asthma Pre-employment NSBR unhelpful in predicting potroom asthma 26 01 2021
Occupational asthma: Cooks are an overlooked group with occupational respiratory symptoms Cooks are an overlooked group with occupational respiratory symptom 09 01 2021
Occupational asthma: New Kim (a femalele racing pigeon,) sells for $1,800,000 New Kim (a femalele racing pigeon,) sells for $1,800,000 11 12 2020
Occupational asthma: Increassed risk of asthma, but also COPD in cleaners, a metaanalysis Increassed risk of asthma, but also COPD in cleaners, a metaanalysis 11 12 2020

Latest Publications

Abstract Available for Chronic obstructive pulmonary disease in older persons: A comparison of two spirometric definitions Fragoso CAV, Concato J, McAvay G, Ness PHV, Rochester CL, Yaggi HK, Gill TM, Chronic obstructive pulmonary disease in older persons: A comparison of two spirometric definitions, Respir Med, 2010;104:1189-1196,https://doi.org/10.1016/j.rmed.2009.10.030

Abstract Available for COPD prognosis in relation to diagnostic criteria for airflow obstruction in smokers Akkermans RP, Biermans M, Robberts B, ter Riet G, Jacobs A, van Weel C, Wensing M, Schermer T, COPD prognosis in relation to diagnostic criteria for airflow obstruction in smokers, Eur Respir J, 2014;43:54-63,DOI: 10.1183/09031936.00158212

Abstract Available for GOLD classifications and mortality in chronic obstructive pulmonary disease: the HUNT Study, Norway Leivseth L, Brumpton BM, Nilsen TIL, Mai X, Johnsen R, Langhamme A, GOLD classifications and mortality in chronic obstructive pulmonary disease: the HUNT Study, Norway, Thorax, 2013;68:914-921,http://dx.doi.org/10.1136/thoraxjnl-2013-203270

Go to "References" section.

Latest Forum Questions

Comments for the paper: "Occupational use of high-level disinfectants and asthma incidence in early- to mid-career female nurses: a prospective cohort study.", 2020, Occup Environ Med
An internet-based study of Canadian and USA nurses relating a report of doctor diagnosed asthma to the question "have you ever used disinfectants to disinfect medical instruements, devices or supplies (such as endoscopes, thermomemeters or other other idems than cannot be sterilised), by manual or automatic methods (does not include cleaning of work surfaces). Small incresed risk of new asthma in those saying yes (RR 1.39 for >5years use)
Published Paper Comments, , 4/7/2021, 4/29/2021,

Comments for the paper: "Occupations and exposure events in acute and subacute irritant-induced asthma", 2021, Occup Environ Med
Table 3 Causative agents of irritant-induced asthma Main groups of causative agents Acute N=30 Subacute N=39 Total N=69 (%) Acid aerosols or fumes 6 Sulfuric acid Hydrofluoric acid Nitric acid Hydrochloric acid Hydrochloric acid and sulfur dioxide 7 Sulfuric acid* and ammonium fluoride Sulfuric acid* and hydrogen sulfide Sulfuric acid*, sulfur dioxide and sulfur trioxide Hydrochloric acid Nitric acid 13 (19) Base aerosols or fumes 5 Ammonia Sodium hydroxide Black lye 4 Ammonia Sodium hydroxide Alkaline epoxy polyamine hardener and cleaning agent 9 (13) Mixtures of acid and base aerosols or fumes 3 Ammonia, sulfuric acid, hydrochloric acid, hydrofluoric acid, nitric acid Sodium hydroxide, potassium hydroxide, sulfuric acid, nitric acid 3 (4) Inorganic gases 3 Chlorine dioxide 3 Chlorine dioxide Chlorine dioxide and hydrogen sulfide Sulfur dioxide 6 (9) Oxidising agents 1 Ozone 1 Hydrogen peroxide 2 (3) Other chemicals 5 Formaldehyde† Glutaraldehyde† Hexamethylene diisocyanate† Naphthalene compounds Pyrethrin 1 Hexamethylene diisocyanate† 6 (9) Mixtures 6 Bitumen, solvents and their thermal degradation products Sodium hydroxide, sodium hypochlorite Combustion gas Thermal degradation of polyester paint Sulfuric acid, sodium hypochlorite, chlorine dioxide gas Nitric oxides, diesel exhaust, mixture of oil and water 12 Ammonia and hydrogen sulfide Ammonia, hydrogen sulfide and endotoxins Hydrogen sulfide, sulfur compounds, sodium hydroxide, chlorine dioxide Calcium oxide and hydrogen sulfide Rubber chemicals and their thermal degradation products Solvents and mine dust Formic acid, acetic acid, formaldehyde Thermal degradation of polyvinyl chloride-polyurethane fabrics Trifluoroacetic acid and acetonitrile 18 (26) Dusts 4 Calcium oxide Cement 4 Ash Calcium oxide and alkaline dusts Cement Sulfuric acid-containing titanium oxide powder 8 (12) Endotoxins 0 4 4 (
Published Paper Comments, , 4/15/2021, 4/25/2021,

Comments for the paper: "Occupational use of high-level disinfectants and asthma incidence in early- to mid-career female nurses: a prospective cohort study.", 2020, Occup Environ Med
An internet-based study of Canadian and USA nurses relating a report of doctor diagnosed asthma to the question "have you ever used disinfectants to disinfect medical instruements, devices or supplies (such as endoscopes, thermomemeters or other other idems than cannot be sterilised), by manual or automatic methods (does not include cleaning of work surfaces). Small incresed risk of new asthma in those saying yes (RR 1.39 for >5years use)
Published Paper Comments, , 4/7/2021, 4/7/2021,

The Website

This website is run by the Oasys research group, part of the Midland Thoracic Society, UK. We are an independent group of clinicians and researchers, and run a clinical service for workers with occupational lung disease as part of the British National Health Service. We have developed the Oasys program to help ourselves and others in the diagnosis of occupational asthma. We have no specific funding, relying on research grants and the enthusiasm of our group. The website is written by Cedd Burge, who receives some funding from the group. The group meets every Friday evening after the occupational lung disease clinic, as shown below.



As a casual user of this site (without logging in or registering) you can view all the information and use all the contact pages. Registered and logged in users (registering is free and we won't abuse your email) can download and use the Oasys program, ask and reply to questions in the forums, leave comments, add new references, add abstracts and full text links to existing references, answer questions in the case histories and provide evidence and suggest questions for future evidence based guidelines.

If you would like to be added to the list of known authors or collaborators then please register with the website (if you have not already done so) and then get in touch from the contact page. Once we have set the page up you will be able to edit it yourself and indicate which references you have written. Your picture will then be displayed along with each of these references. If you are already in these lists and would like to edit your page then please register with the website and then get in touch from the contact page.

Funding

Recent research grants / contracts have been received from the following.

The Oasys Team

Wasif Anees, Oasys Anees, Wasif (Oasys)
John Belcher, Oasys Belcher, John (Oasys)
Phil Bright, Oasys Bright, Phil (Oasys)
Cedd Burge, Oasys Burge, Cedd (Oasys)
Geraldine Burge, Birmingham Heartlands Hospital Burge, Geraldine (Birmingham Heartlands Hospital)
Sherwood Burge, Oasys Burge, Sherwood (Oasys)
Celia Catton, Oasys Catton, Celia (Oasys)
Vicki Drought, Oasys Drought, Vicki (Oasys)
Angela Evans, ARTP Evans, Angela (ARTP)
Paul Gannon, Dupont Gannon, Paul (Dupont)
Mike Hendy, Oasys Hendy, Mike (Oasys)
Chris Huntley, University Hospitals Birmingham Huntley, Chris (University Hospitals Birmingham)
John Jackson, Jackson Hocking Limited, UK Jackson, John (Jackson Hocking Limited, UK)
Sarah Manney, Birmingham Heartlands Hospital Manney, Sarah (Birmingham Heartlands Hospital)
Jennifer McCoach (now Croft), Oasys McCoach (now Croft), Jennifer (Oasys)
Emmet McGrath, Oasys McGrath, Emmet (Oasys)
David Miedinger, Lucern, Basel and Montreal Miedinger, David (Lucern, Basel and Montreal)
Vicky Moore, Oasys Moore, Vicky (Oasys)
Darren Newton, Oasys Newton, Darren (Oasys)
Charles Pantin, Keele, UK Pantin, Charles (Keele, UK)
Edward Parkes, Birmingham Heartlands Hospital Parkes, Edward (Birmingham Heartlands Hospital)
Alastair Robertson, Selly Oak Hospital Robertson, Alastair (Selly Oak Hospital)
Arun Dev Vellore, Oasys Vellore, Arun Dev (Oasys)
Gareth Walters, Heartlands Walters, Gareth (Heartlands)

Collaborators

Hille Suojalehto, Finnish Institute of Occupational Health Suojalehto, Hille (Finnish Institute of Occupational Health)
Irmeli Lindstrom, Finnish Institute of Occupational Health Lindstrom, Irmeli (Finnish Institute of Occupational Health)
Vivi Schlunssen, Aarhus Schlunssen, Vivi (Aarhus)
Martin Miller, Selly Oak Hospital, Birmingham Miller, Martin (Selly Oak Hospital, Birmingham)
Maritta Jaakkola, Oulu University Finland Jaakkola, Maritta (Oulu University Finland)
Henrik Nordman, Finnsh Institute of Occupational Health Nordman, Henrik (Finnsh Institute of Occupational Health)
Tony Newman Taylor, Royal Brompton Hospital, London Newman Taylor, Tony (Royal Brompton Hospital, London)
Paul Cullinan, Royal Brompton Hospital, London, UK Cullinan, Paul (Royal Brompton Hospital, London, UK)
Julie Cannon, Royal Brompton Hospital London Cannon, Julie (Royal Brompton Hospital London)
Jo Feary, Royal Brompton Hospital Feary, Jo (Royal Brompton Hospital)

Known Authors

T Rochat, Geneva Rochat, T (Geneva)
Oyvind Omland, Aahus Denmark Omland, Oyvind (Aahus Denmark)
Torben Sigsgaard, University of Aarhus Sigsgaard, Torben (University of Aarhus)
Ilenia Folletti, Perugia Folletti, Ilenia (Perugia)
Martin Seed, Manchester University Seed, Martin (Manchester University)
Garry Liss, Toronto Liss, Garry (Toronto)
Susan Tarlo, Toronto Tarlo, Susan (Toronto)
Jeroen Douwes, Massey University, Wellington, NZ Douwes, Jeroen (Massey University, Wellington, NZ)
Jouni Jaakkola, Institute of Occupational and Environmental Medicine, Birmingham Jaakkola, Jouni (Institute of Occupational and Environmental Medicine, Birmingham)
Joaquin Sastre, Fundacion Jimenez Diaz, Madrid Sastre, Joaquin (Fundacion Jimenez Diaz, Madrid)

Oasys and occupational asthma smoke logo