If the Mayo histology of your Lung biopsy shows hypersensitivity pneumonitis, this is probably the correct diagnosis, it doesnt however give any clue to the cause. If your breathing problems started after you got rid of the cockatoo, it would be an unlikely cause of your HP. Dental technicians are at risk of a large number of occupational lung diseases, particularly asthma (from acrylates and latex amongst others) and silicosis (from sand blaasting). Some of the metals may also cause asthma, particularly chrome. HP is not common, but cobalt can cause a similar disease (giant cell intersitial pneumonitis, GIP). If your symptoms started while working as a dental technician, and particularly if you got better and worse with work exposures (at least at the beginning) it would be worth rechecking the biopsy for GIP. Finally from a treatment point of vie there is some suggestion that Retuximab may help when all else has failed.
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Lota HK, Keir GJ, Hansell DM, Nicholson AG, Maher TM, Wells AU, Renzoni EA,
Novel use of rituximab in hypersensitivity pneumonitis refractory to conventional treatment,
Thorax,
2013;68:780-781,
|
|
|
|
|
|
Piirilä P, Hodgson U, Estlander T, Keskinen H, Saalo A, Voutilainen R, Kanerva L,
Occupational respiratory hypersensitivity in dental personnel,
Int Arch Occup Environ Health,
2002;75:209-216,
|
|
|
|
|
|
Piirila P, Kanerva L, Keskinen H, Estlander T, Hytonen M, Tuppurainen M, Nordman H,
Occupational respiratory hypersensitivity caused by preparations containing acrylates in dental personnel,
Clin Exp Allergy,
1998;28:1404-1411,
|
|
|
|
|
|
Choudat D, Triem S, Weill B, Vicrey C, Ameille J, Brochard P, Letourneux M, Rossignol C,
Respiratory symptoms, lung function, and pneumoconiosis among self employed dental technicians,
Brit J Industr Med,
1993;50:443-449,
|
|
|
|
|
|