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Occupational asthma cause by Triclosan, a biocide used by a nursery nurse; new cause

Occupational asthma cause by Triclosan, a biocide used by a nursery nurse; new cause
A recent consensus statement has highlighted the increased risk of developing asthma after exposure to workplace and domestic cleaning products. Specific cleaning agents, such as benzalkonium chloride, have been recognized as causes of occupational asthma by sensitization, but chlorine-releasing products are in more common use and are associated with asthma in epidemiological studies. More commonly the cause are chloramines produced when chlorine reacts with a nitrogen source. There are very few positive specific challenges to chlorine-releasing products alone, this is one of them.

References

Abstract Available for Occupational asthma caused by sensitization to a cleaning product containing triclosan, Antibac, (2,4,4’-trichloro-2’-hydroxydiphenyl ether), nurse, cleaner, Walters GI, Robertson AS, Moore VC, Burge PS, Occupational asthma caused by sensitization to a cleaning product containing triclosan, Antibac, (2,4,4’-trichloro-2’-hydroxydiphenyl ether), nurse, cleaner, , Ann Allergy Asthma Immunol, 2017;118:370-371,http://doi.org/10.1016/j.anai.2016.12.001
Sherwood Burge, Oasys, an author of 'Occupational asthma caused by sensitization to a cleaning product containing triclosan, Antibac, (2,4,4’-trichloro-2’-hydroxydiphenyl ether), nurse, cleaner,' Vicky Moore, Oasys, an author of 'Occupational asthma caused by sensitization to a cleaning product containing triclosan, Antibac, (2,4,4’-trichloro-2’-hydroxydiphenyl ether), nurse, cleaner,' Alastair Robertson, Selly Oak Hospital, an author of 'Occupational asthma caused by sensitization to a cleaning product containing triclosan, Antibac, (2,4,4’-trichloro-2’-hydroxydiphenyl ether), nurse, cleaner,' Gareth Walters, Heartlands, an author of 'Occupational asthma caused by sensitization to a cleaning product containing triclosan, Antibac, (2,4,4’-trichloro-2’-hydroxydiphenyl ether), nurse, cleaner,'

Abstract Available for What causes occupational asthma in cleaners? Moore VC, Burge PS, Robertson AS, Walters GI, What causes occupational asthma in cleaners?, Thorax, 2017;72:581–583.,org/10.1136/ thoraxjnl-2016-208827
Sherwood Burge, Oasys, an author of 'What causes occupational asthma in cleaners?' Vicky Moore, Oasys, an author of 'What causes occupational asthma in cleaners?' Alastair Robertson, Selly Oak Hospital, an author of 'What causes occupational asthma in cleaners?' Gareth Walters, Heartlands, an author of 'What causes occupational asthma in cleaners?'

Abstract Available for Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement Siracusa A, De Blay F, Folletti I, Moscato G, Olivieri M, Quirce S, Raulf-Heimsoth M, Sastre J, Tarlo SM, Walusiak-Skorupa J, Zock J-P, Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement, Allergy, 2013;68:1532-1545,
Frederic de Blay, Hopital Universitaires de Strasbourg, an author of 'Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement' Joaquin Sastre, Fundacion Jimenez Diaz, Madrid, an author of 'Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement' Giana Moscato, Fondazione Salvatore Maugeri, Pavia, an author of 'Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement' Santiago Quirce, Madrid, an author of 'Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement' Andrea Siracusa, Perugia, an author of 'Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement' Susan Tarlo, Toronto, an author of 'Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement' Jan-Paul Zock, Municipal Institute of Medical Research, Barcelona, Spain, an author of 'Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement' Ilenia Folletti, Perugia, an author of 'Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement' Jolanta Walusiak, Lodz, an author of 'Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement' Monika Raulf-Heimsoth, Bochum, an author of 'Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement'

Abstract Available for Airway response to chlorine inhalation (bleach) among cleaning workers with and without bronchial hyperresponsiveness Sastre J, Madero MF, Fernández-Nieto M, Sastre B, del Pozo V, Potro MG, Quirce S, Airway response to chlorine inhalation (bleach) among cleaning workers with and without bronchial hyperresponsiveness, Am J Industr Med, 2011;54:293-299,
Joaquin Sastre, Fundacion Jimenez Diaz, Madrid, an author of 'Airway response to chlorine inhalation (bleach) among cleaning workers with and without bronchial hyperresponsiveness' Santiago Quirce, Madrid, an author of 'Airway response to chlorine inhalation (bleach) among cleaning workers with and without bronchial hyperresponsiveness'

Comments

A recent consensus statement has highlighted the increased risk of developing asthma after exposure to workplace and domestic cleaning products. Specific cleaning agents, such as benzylalkonium chloride, have been recognized as causes of occupational asthma by sensitization and now comprise a significant burden of work-related asthma. Chlorine-releasing products commonly cause asthma via the production of chloramines, requiring a protein source in addition to the biocide. There are very few positive specific challenges to a chlorine-releasing biocide alone, this is one of them.
6/4/2017

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