Occupational asthma cause by Triclosan, a biocide used by a nursery nurse; new cause |
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A recent consensus statement has highlighted the increased risk of developing asthma after exposure to workplace and domestic cleaning products. Specific cleaning agents, such as benzalkonium chloride, have been recognized as causes of occupational asthma by sensitization, but chlorine-releasing products are in more common use and are associated with asthma in epidemiological studies. More commonly the cause are chloramines produced when chlorine reacts with a nitrogen source. There are very few positive specific challenges to chlorine-releasing products alone, this is one of them.
References
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Walters GI, Robertson AS, Moore VC, Burge PS,
Occupational asthma caused by sensitization to a cleaning product containing triclosan, Antibac, (2,4,4’-trichloro-2’-hydroxydiphenyl ether), nurse, cleaner, ,
Ann Allergy Asthma Immunol,
2017;118:370-371,http://doi.org/10.1016/j.anai.2016.12.001
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Siracusa A, De Blay F, Folletti I, Moscato G, Olivieri M, Quirce S, Raulf-Heimsoth M, Sastre J, Tarlo SM, Walusiak-Skorupa J, Zock J-P,
Asthma and exposure to cleaning products – a European Academy of Allergy and Clinical Immunology task force consensus statement,
Allergy,
2013;68:1532-1545,
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Sastre J, Madero MF, Fernández-Nieto M, Sastre B, del Pozo V, Potro MG, Quirce S,
Airway response to chlorine inhalation (bleach) among cleaning workers with and without bronchial hyperresponsiveness,
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2011;54:293-299,
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Comments
A recent consensus statement has highlighted the increased risk of developing asthma after exposure to workplace and domestic cleaning products. Specific cleaning agents, such as benzylalkonium chloride, have been recognized as causes of occupational asthma by sensitization and now comprise a significant burden of work-related asthma. Chlorine-releasing products commonly cause asthma via the production of chloramines, requiring a protein source in addition to the biocide. There are very few positive specific challenges to a chlorine-releasing biocide alone, this is one of them.
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