Adipic Acid

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This table is produced from a case report of one patient who had occupational asthma to colophony-free solder wire containing an adipic acid flux. Adipic Acid has been previously suggested as a cause of occupational asthma in a pharmaceutical factory worker who was in contact with spiramycin powder 1.

Agent Adipic Acid
Job Solderer / Desolderer
Specific IgE not done
Skin prick test not done
Non-specific reactivity
Serial Peak Flow Positive
Induced sputum not done
FENO not done
Specific Challenge

Positive, late reaction with change in methacholine from 3450 to 1729 pre test to post.

Follow-up

Changed jobs, asthma continued, methacholine > 4800

Substitutions Other colophony free solders

References for: Adipic Acid See published papers on "Adipic Acid" from this website.
Haz-Map information on: Adipic Acid See information on "Adipic Acid" from the HazMap (Information on Hazardous Chemicals and Occupational Diseases) website.

Oasys Notifications for Adipic Acid

The Oasys Audit scheme started midway through 2010 and collects agents typed in through the Oasys program. The years before 2010 show old data entered during 2010 or later and are likely to have many fewer notifications. We expect Oasys to become more widely adopted as time goes by so increasing notifications does not necessarily mean an increasing problem.

Occupational asthma notifications to the Oasys Audit Scheme for Adipic Acid

Selected References for Adipic Acid

Abstract Available for Occupational asthma to solder wire containing an adipic acid flux Moore VC, Burge PS, Occupational asthma to solder wire containing an adipic acid flux , Eur Respir J, 2010;36:962-963,
Sherwood Burge, Oasys, an author of 'Occupational asthma to solder wire containing an adipic acid flux' Vicky Moore, Oasys, an author of 'Occupational asthma to solder wire containing an adipic acid flux'

Abstract Available for Bronchial asthma due to spiramycin and adipic acid Moscato G, Naldi L, Candura F, Bronchial asthma due to spiramycin and adipic acid, Clin Allergy, 1984;14:335-361,
Giana Moscato, Fondazione Salvatore Maugeri, Pavia, an author of 'Bronchial asthma due to spiramycin and adipic acid'

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