How big are the changes in PEF in non-symptomatic workers exposed regularly to high levels of a respiratory irritant? |
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A study of grain dockers and farmers during grain harvest exposed to levels >30mg/m
3 showed that the 95% CI for mean restday minus worday PEF was 16 litres/min; a similar 95% CI was found in non-occupational asthmatics. Using this cut-off this index gave a sensitivity of 68% for the diagnosis of occupational asthma (with a pre-defined specificity of 95%)
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