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How big are the changes in PEF in non-symptomatic workers exposed regularly to high levels of a respiratory irritant?

How big are the changes in PEF in non-symptomatic workers exposed regularly to high levels of a respiratory irritant?
A study of grain dockers and farmers during grain harvest exposed to levels >30mg/m3 showed that the 95% CI for mean restday minus worday PEF was 16 litres/min; a similar 95% CI was found in non-occupational asthmatics. Using this cut-off this index gave a sensitivity of 68% for the diagnosis of occupational asthma (with a pre-defined specificity of 95%)

References

Full Text Available for Differentiating occupational asthmatics from non-occupational asthmatics and irritant-exposed workers Anees W, Blainey D, Moore VC, Robertson K, Burge PS, Differentiating occupational asthmatics from non-occupational asthmatics and irritant-exposed workers, Occup Med, 2011;61:191-195,
David Blainey, Essex, UK, an author of 'Differentiating occupational asthmatics from non-occupational asthmatics and irritant-exposed workers' Sherwood Burge, Oasys, an author of 'Differentiating occupational asthmatics from non-occupational asthmatics and irritant-exposed workers' Wasif Anees, Oasys, an author of 'Differentiating occupational asthmatics from non-occupational asthmatics and irritant-exposed workers' Vicky Moore, Oasys, an author of 'Differentiating occupational asthmatics from non-occupational asthmatics and irritant-exposed workers'

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