Irritant induced asthma in the film industry

I have a patient who seems to have irritant-induced asthma (arguably "RADS")from the highly-irritant materials using in making the sets (he is a carpenter) but that really means plastics, etc, rather than wood. Lots of styrene, various alcohols, acetates, ketones, toluene - all in high concentration. Do you have any good references for this? We are unable to get compensation for irritant asthma (RADS) unless it fulfills the original Brooks criteria Do you have any references related to the film industry?

Occupational Asthma, Specialist, 5/27/2010, 5/27/2010,

I think that the differences between occupational asthma due to sensitisation and due to "low" dose irritation with latency is largely artificial and relates more to the prejudices of the reporter than do anything that can be measured. The only paper on low dose irritation rather artificially restricts the length of symptomless exposure and doesnt separate those with regular deterioration with usual exposure, and those who have no work-related changes from usual exposure (as in rads). There are some reports of styrene induced occupational asthma Burge PS, Robertson AS, Cullinan P, Howell TJ, Obliterative Bronchiolitis in Boatbuilders Exposed to Styrene and Isocyanates, Am J Respir Crit Care Med, 2008;177:a157, Fernández-Nieto M, Quirce S, Fraj J, del Pozo V, Seoane C, Sastre B, Lahoz C, Sastre J, Airway inflammation in occupational asthma caused by styrene, J Allergy Clin Immunol, 2006;117:248-250, Volkman KK, Merrick JG, Zacharisen C, Yacht-makers lung: a case of hypersensitivity pneumonitis in yacht manufacturing, Wisconsin Medical Journal, 2006;105:47-50, Kujala V, Niinimaki A, Occupational induction of hypersensitivity after an accidental exposure to chloromethylisothiozolinone and methylisothiozolinone (CMI/MI) in an industrial worker, Occup Med, 1999;49:51-53, Brooks SM, Hammad Y, Richards I, Giovinco-Barbas J, Jenkins K,, The spectrum of irritant-induced asthma: sudden and not-so-sudden onset and the role of allergy, Chest, 1998;113:42-49, Grammer LC, Shaughnessy MA, Henderson J, Zeiss CR, Kavich DE, Collins MJ, Pecis KM, Kenamore BD, A clinical and immunologic study of workers with trimellitic-anhydride-induced immunologic lung disease after transfer to low exposure jobs, Am Rev Respir Dis, 1993;148:54-57, Hayes JP, Lambourn L, Hopkirk JAC, Durham SR, Newman Taylor AJ, Occupational asthma due to styrene, Thorax, 1991;46:396-397, Moscato G, Marraccini P, Dellabianca A, Vinci G, Occupational asthma and rhinitis due to styrene, Clin Exp Allergy, 1990;20 suppl 1:45-45, Moscato G, Biscaldi G, Cottica D, Pugiese F, Candura S, Candura F, Occupational asthma due to styrene, two case reports, J Occup Med, 1987;29:*-*, Brooks SM, Weiss MA, Bernstein IL, Reactive airways dysfunction syndrome (RADS). Persistent asthma syndrome after high level irritant exposure, Chest, 1985;88:376-384, Jedrychowski W, Styrene and methylmethacrylate in the industrial environment as a risk factor of chronic obstructive lung disease, Int Arch Occup Environ Health, 1982;51:151-157, Brooks SM, Vandevort R, Polyvinylchloride film thermal decomposition products as an occupational illness, J Occup Med, 1977;19:192-196, Lorimer WV, Lilis R, Nicholson WJ, Anderson H, Fischbein A, Daum S, Rom W, Rice C, Selikoff IJ, Clinical studies of styrene workers: initial findings, Environ Health Perspect, 1976;17:171-181,

5/27/2010