Occupational Asthma Reference

Choi G-S, Sung J-M, Lee J-W, Ye Y-M, Park H-S, A case of occupational asthma caused by inhalation of vancomycin powder, Allergy, 2009;64:1391-1392,

Keywords: korea, new cause, vancomycin,asthma, rhinitis, pharmaceutical manufacturer, case report, NSBR, peak flow, IgE negative, basophil histamine release

Known Authors

Hae-Sim Park, Korea Hae-Sim Park

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Abstract

A pharmacetical worker who developed occupational asthma and rhinitis 5 months after starting purification of vancomycin powder. Positive peak flow and history, refused specific challenge. IgE and skin prick testing to vancomycin negative, but strong basophil histamine release using HSA conjugate (negative in controls). Authors suggest that the mechanism is direct histamine release

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Comments

evidence table


			Vancomycin manufacture, a new cause of OA acting by direct histamine release?

12/18/2009

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