Occupational asthma to gel flux containing dodecanedioic acid (new cause)

Agent	Dodecanedioic acid
Job	Soldering Instructor
Specific IgE	not done
Skin prick test	not done
Non-specific reactivity	Pre challenge >4800µg methacholine (Yan technique), becoming measurable post challenge at 3490µg.
Serial Peak Flow	positive oasys score
Induced sputum	not done
FE_NO	14.3ppb (Aerocrine Niox) while exposed (normal); 10.7ppb away from exposure
Specific Challenge	Specific bronchial challenge showing dual reaction to heated gel flux containing dodecanedioic acid, no reaction to colophony flux. Reaction lasted 12 hours.
Follow-up	improved on removal from exposure

References

	Moore VC, Manney S, Vellore, Burge PS, Occupational asthma to gel flux containing dodecanedioic acid, Allergy, 2009;64:1099-1100,

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