Super Categories
Subcategories
None
Known Synonyms
anaesthetic gases
halothane
Isoflourane
isofluorane
isoflurane
isolfurane, seveoflurane
Sevoflourane
sevoflurane
Table below is from one case report of a patient with occupational asthma. Specific Inhalation Challenge to anaesthetic agents is tricky as an anaesthetist needs to be present and the patient needs to stay awake.
| Agent |
Anaesthetic agents (isoflourance and sevoflourane)
|
| Job |
Anaesthetic assistant and nurse mostly exposed in recovery areas |
| Specific IgE |
|
| Skin prick test |
|
| Non-specific reactivity |
normal before challenge for 3 out of 3 patients and reactive in 3 out of 3 patients post challenge.
|
| Serial Peak Flow |
1 positive, 1 equivocal and 1 not done
|
| Induced sputum |
|
| FENO |
|
| Specific Challenge |
late reaction to isoflurane and sevoflurane 15 breaths 0.5% (1); late
reaction isoflurane alone 18 breaths 0.5% (1); rash and nsbr decline
isoflurane alone 18 breaths 0.5% (1); controls no reaction |
| Follow-up |
Better after relocation away from recovering post-op patients exhaling
anaesthetic gasses. One had anaphylactic reaction during a general
anaesthetic using sevoflurane |
Oasys Notifications for Anaesthetic Agents
The Oasys Audit scheme started midway through 2010 and collects agents typed in through the Oasys program. The years before 2010 show old data entered during 2010 or later and are likely to have many fewer notifications. We expect Oasys to become more widely adopted as time goes by so increasing notifications does not necessarily mean an increasing problem.
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Selected References for Anaesthetic Agents
 |
Vellore AD, Drought VJ, Sherwood-Jones D, Tunnicliffe B, Moore VC, Robertson AS, Burge PS,
Occupational asthma and allergy to sevoflurane and isoflurane in anaesthetic staff,
Allergy,
2006;61:1485-6,
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