What are the sensitivity and the specificity of specific IgE testing in the diagnosis of validated cases of occupational asthma?


** 2+ Skin prick tests are highly sensitive but less specific for occupational asthma caused by complex platinum salts.

Evidence

Merget R, Dierkes A, Rueckmann A, Bergmann EM, SchultzeWerninghaus G , Absence Of Relationship Between Degree Of Nonspecific And Specific Bronchial Responsiveness In Occupational Asthma Due To Platinum Salts , Eur Respir J , 1996 ; 9 : 211-216

Merget R, SchultzeWerninghams G, Bode F et al , Quantitative Skin Prick And Bronchial Provocation Tests With Platinum Salt , Br J Ind Med , 1991 ; 48 : 830-837

Merget R, SchultzeWerninghaus G, Muthorst T et al , Asthma Due To The Complex Salts Of Platinum: A Cross-Sectional Survey Of Workers In A Platinum Refinery , Clin Allergy , 1988 ; 18 : 569-580

Vedal S, ChanYeung M, Enarson DA et al , Plicatic Acid-Specific Ige And Nonspecific Bronchial Hyper-responsiveness In Western Red-Cedar Workers , J Allergy Clin Immunol , 1986 ; 78 : 1103-1109


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