Occupational Asthma Reference
|
Aleva RM, Aalbers R, Koeter GH, De Monchy JG,
Occupational asthma caused by a hardener containing an aliphatic and a cycloaliphatic diamine,
Am Rev Respir Dis,
1992;145:1217-1218,
|
|
|
Keywords: oa, as , bal, eosinophil, amine, case report, paint, floor sealant, salesman, pat, isophoronediamine, trimethyl-1 6-hexanediamine, nc, epoxy
Known Authors
If you would like to become a known author and have your picture displayed along with your papers then please get in touch from the contact page. Known authors can choose to receive emails when their papers receive comments.
Abstract
An otherwise healthy 44-yr-old man experienced a serious attack of bronchial obstruction after working with resins and hardeners, releasing fumes of a mixture of an alipathic and a cycloaliphatic diamine hardener. Eight hours after deliberate challenge with the hardener a large increase of airway resistance was found. Seventy-two hours after challenge, eosinophilia in the bronchoalveolar lavage (BAL) fluid together with a decrease of peripheral eosinophils was seen. After cessation of contact with this hardener, no more acute episodes occurred, although maintenance treatment with a topical corticosteroid and a beta 2-agonist remained necessary. A BAL performed 1 yr later showed a normal cell distribution. The results suggest that these aliphatic and cycloaliphatic diamine hardeners may be occupational hazards. Eosinophil inflammation may play a causal role
Full Text
Full text of this reference not available
Please Log In or Register to add the full text to this reference
Comments
Please sign in or register to add your thoughts.