Occupational Asthma Reference

Wortong D, Chaiear N, Boonsawat W, Risk of asthma in relation to occupation: A hospital-based case-control study, Asian Pacific Journal of allergy and Immunology, 2015;33:152-160,

Keywords: Thailand, epidemiology, causes, healthcare, textiles, school, case control

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Naesinee Chaiear, Khon Kaen University, Thailand Naesinee Chaiear

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Asthma is a common occupational lung disease and is preventable by removing identifiable allergens.

(1) To assess the relationship between occupation and asthma
(2) To determine the agents associated with asthma

This hospital-based, case-control study interviewed 153 cases from the Asthma Clinic and 306 non-asthmatic controls from Srinagarind Hospital, Thailand. Crude odds ratios (COR), 95% confidence intervals (95% CI) and adjusted ORs (AOR) for multiple logistic regression were calculated.

The 153 cases, 70.6% were females with median age of 53 (IQR-14). The 306 controls 62.4% were females with median age of 56 (IQR-16). The highest risk of asthma was family history of asthma and history of atopy [AOR 11.16 (95% CI 4.33, 28.74) and AOR 8.03 (95% CI 4.90, 13.19)], respectively. If only occupations were considered, healthcare workers had the highest risk [AOR 4.08 (95% CI 1.35, 12.30)] followed by textile workers [AOR 3.34 (95% CI 1.07, 10.47)] and school workers AOR 2.40 (95% CI 1.31, 4.41). When subgroups of non-atopy were considered, school workers had a significant association with asthma [COR 3.18 (95% CI 1.48, 6.83)]. When no family history of asthma was considered, school and textile workers had the most significant association with asthma [COR 3.10 (95% CI 1.87, 5.13) and COR 3.06 (95% CI 1.15, 8.13), respectively]. Inorganic dust was the agent most significantly associated with asthma (COR 1.89 (95% CI 1.25, 2.82).

School textile and healthcare workers had the greatest risk of asthma. Family history of asthma and being atopic would also promote asthma in relation to occupation.

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