Occupational Asthma Reference

Harrison J, Pickering CAC, Faragher EB, Austwick PKC, Little SA, Lawton L, An investigation of the relationship between microbial and particulate air pollution and the sick building syndrome, Respir Med, 1992;86:225-235,

Keywords: am, sbs, microbiology, air-conditioning, nv, dust, bacteria, fungae, ep, cross sectional

Known Authors

Tony Pickering, Wythenshawe Hospital, Manchester, UK Tony Pickering

John Harrison, Hammersmith Hospital, London John Harrison

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The sick building syndrome has been the subject of research for approximately 10 years. Although it is often suggested that symptoms in office workers are due to circulating micro-organisms or particles, epidemiological studies investigating the relationship between them have been lacking. This cross-sectional study has combined medical and aerobiological assessments of offices in Great Britain and has found that, although airborne particulates and micro-organisms are unlikely to be the sole cause of the sick building syndrome, positive associations between symptom prevalence rates and levels of airborne viable bacteria and fungi within groups of buildings with similar ventilation systems, suggest a possible causal link that should be explored.

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