Occupational Asthma Reference

Smedley J, Jury A, Bendall H, Frew A, Coggon D, The prevalence and risk factors for latex allergy: a cross-sectional study in a UK hospital, Occup Environ Med, 1999;56:833-836,

Keywords: latex, health-care worker, prock test, prevalence, urticaria,

Known Authors

David Coggon, Southampton University David Coggon

Julia Smedley, Southampton University Hospital Julia Smedley

Tony Frew, Brighton Tony Frew

If you would like to become a known author and have your picture displayed along with your papers then please get in touch from the contact page. Known authors can choose to receive emails when their papers receive comments.


OBJECTIVES: To determine the prevalence and risk factors for symptoms related to gloves, and the relation between symptoms and immunological evidence of type 1 hypersensitivity to latex in a United Kingdom health care setting.
METHODS: A cross sectional survey was carried out among 773 employees at a British hospital. A self administered questionnaire was used to collect information about symptoms related to gloves and associated risk factors in a sample of hospital staff who were likely to use gloves at work. All of those who reported symptoms suggestive of type 1 hypersensitivity were invited for skin prick testing and measurement of specific IgE to latex (RAST).
RESULTS: Among the 372 responders, symptoms related to gloves were common, 49% reported redness or itching of the hands, 14% reported urticaria, and 6% reported chest tightness. However, the frequency of positive skin prick tests and RASTs was surprisingly low (only two subjects tested positive).
CONCLUSIONS: These findings indicate the need for caution in the interpretation of symptoms related to gloves even when they seem to suggest type 1 hypersensitivity.

Full Text


Please sign in or register to add your thoughts.

Oasys and occupational asthma smoke logo