Occupational Asthma Reference

Cimarra M, MartinezCocera C, Chamorro M, Cabrera M, Robledo T, Lombardero M, Alonso A, Catellano A, Bartolome JM, Occupational asthma caused by champignon flies, Allergy, 1999;54:521-525,

Keywords: Spain, oa, fly, mushroom, Phoridae brachycera, Sciaridae nematocera, IgE, prick test, challenge, rhinitis, conjunctivitis, nc, symptoms

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Abstract

BACKGROUND: Occupational bronchial asthma in mushroom (champignon) workers is unusual, although reports on it appeared in 1938 and 1951; we have not found any others since those dates. Here we report the case of a 52-year-old man who works as a champignon cultivator. He suffered rhinoconjunctivitis and asthma attacks whenever he entered the champignon culture caves. We studied flies as a possible antigen source. We collected these insects from the growing sites in order to identify them, and then prepare an extract; the samples turned out to be of two families of insects of the order Diptera, 98% from the Phoridae family (Brachycera suborder) and 2% from the Sciaridae (Nematocera suborder).

METHODS: Skin prick tests, conjunctival provocation tests, serum specific IgE, specific IgE-binding fractions in immunoblotting, and monitoring of PEFR (at work and off work) were performed.

RESULTS: IgE-mediated hypersensitivity to these flies was demonstrated by skin prick test, conjunctival provocation test, serum specific IgE, and IgE-binding fractions in immunoblotting. Monitoring of PEFR both at work and off work showed a clear relationship between symptoms, or fall in PEFR, and the workplace.

CONCLUSIONS: We report the case of a patient suffering from asthma and rhinoconjunctivitis caused by hypersensitivity to fly proteins

Occupational Asthma Reference

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