Occupational Asthma Reference
Leroyer C, Perfetti L, Cartier A, Malo JL,
Can reactive airways dysfunction syndrome (RADS) transform into occupational asthma due to "sensitisation" to isocyanates?,
Thorax,
1998;53:152-153,
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Keywords: Canada, rads, oa, isocyanate, irritant, challenge
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Abstract
The case history is described of a worker who presented with a history suggestive of reactive airways dysfunction syndrome which occurred after an acute high level inhalation of diphenylmethane diisocyanate. Further exposure at work, at a time when concentrations of isocyanates were no longer "irritant", suggested occupational asthma; this diagnosis was confirmed by a specific inhalation challenge test
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