Occupational Asthma Reference
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Yokota T, Hasegawa T, Murakami S, Kurashige K, Maruyama M, Satoh M, Suzuki E, Arakawa M,
Hard metal lung with diffuse small nodular shadows [Japanese],
Nippon Kyobu Shikkan Gakkai Zasshi,
1996;34:465-470,
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Keywords: case report, Japan, hard metal, bal, ct, tungsten carbide, cobalt, alveolitis
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Abstract
A 32-year-old woman was admitted to Niigata University Hospital with dyspnea and a non-productive cough. She had been exposed to hard metal dust for 4 years in a metal-polishing factory. Chest X-ray and CT films showed diffuse small nodular shadows in both lung fields and pulmonary-function tests revealed severe restrictive impairment. Specimens obtained by thoracoscopic lung biopsy showed fibrosis in the centers of lobules and in peribronchiolar regions. Giant-cell interstitial pneumonia-like findings were also noted. Tungsten carbide and cobalt were detected in these specimens, with an X-ray microanalyzer. Hard metal lung was diagnosed. By 1 year after she changed her place of work and began corticosteroid treatment her symptoms and pulmonary function had improved remarkably, although shadows on chest X-ray films remained to some extent
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