Occupational Asthma Reference

Burge PS, Johnson WS, Hayward AR, Neutrophil pyruvate kinase deficiency with recurrent staphylococcal infections: first reported case, Br Med J, 1976;1:742-745,

Keywords: pyruvate kinase, bronchiectasis, nc, case report

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Sherwood Burge, Oasys Sherwood Burge

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A woman with an intracellular killing defect in the neutrophils had neutrophil pyruvate kinase deficiency. She had had recurrent staphylococcal infections throughout her life. The enzyme present was unstable and its kinetics were abnormal

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