Occupational Asthma Reference

Goodman GB, Kaplan PD, Stachura I, Castranova V, Pailes WH, Lapp NL, Acute silicosis responding to corticosteroid therapy, Chest, 1992;101:366-370,

Keywords: silicosis, tr

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Abstract

The course of acute silicosis usually is relentlessly progressive. Death results from cor pulmonale and respiratory failure, with mycobacterial infection a frequent serious complication. Attempts to treat the illness generally have been unavailing. We report an unusual case of acute silicosis in which improvement in clinical status, chest x-ray film findings and pulmonary function occurred following therapy with corticosteroids. To our knowledge, this is the first such case reported in the medical literature

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