Occupational Asthma Reference
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Usui Y, Aida H, Kimula Y, Miura H, Takayama S, Nakayama M,
Hypersensitivity pneumonitis induced by hexamethylene diisocyanate,
Intern Med,
1992;31:912-916,
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Keywords: alveolitis, HDI, bal, case report
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Abstract
A case of hypersensitivity pneumonitis (HP) induced by hexamethylene diisocyanate (HDI) is described. Serial determinations of the lymphocyte surface phenotypes by two-color assay revealed the following: 1) increased activated cytotoxic T lymphocytes in the bronchoalveolar lavage fluid (BALF), and 2) increased percentage and absolute number of non-major histocompatibility complex (MHC)-restricted natural killer (NK) cells in the peripheral blood (PB) during the recovery phase of the disease. These findings were considered to be related to the activity of the disease
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