Occupational Asthma Reference
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BarSela S, Teichtahl H, Lutsky I,
Occupational asthma in poultry workers,
J Allergy Clin Immunol,
1984;73:271-275,
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Abstract
16 poultry workers with poultry house realted rhinitis and/or asthma underwent clincial and laboratory evaluation that included history and physical examination, skin tests with common inhalant and PAg, total and specific IgE levels, and pulmonary-function studies. 16 age and sex matched atopic subjects who were not occupationally exposed to poultry and 12 asymptomatic veterinarians with occupational exposure to poultry served as controls. Rhinitis and asthma developed only in symptomatic poultry workers after exposure to poultry: only in these individuals could immediate wheal and flare reactions to poultry antigens be detected (p < 0.001). The elapsed time between the initial poultry exposure and the onset of poultry house related symptoms average 10 years. In the symptomatic poultry workers, immediate skin test reactivity and RAST reactions were most frequently associated with NFM. The association between respiratory symptoms temporally related to poultry house exposure and the demonstrable IgE antibody mediated reaction suggests a relationship between the two.
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