Occupational Asthma Reference

Malo JL, Cartier A, Gagnon G, Evans S, Dolovich J, Isolated late asthmatic reaction due to nickel sulphate without antibodies to nickel, Clin Allergy, 1985;15:95-99,

Keywords: oa, as , nickel, IgE-, ch, pt-

Known Authors

André Cartier, Hôpital de Sacré Coeur, Montreal, Quebec, Canada André Cartier

Jean-Luc Malo, Hôpital de Sacré Coeur, Montreal, Quebec, Canada Jean-Luc Malo

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A worker with occupational exposure to nickel developed asthma a few months after starting work. Skin prick tests to nickel sulphate were negative. Inhalation challenge with nickel sulphate, at a concentration of 10 mg/ml for 30 min induced a late asthmatic reaction, starting 3 hr after the end of exposure leading to severe nocturnal attack. Tests for antibodies with nickel reactivity were negative.

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