Occupational Asthma Reference

Brock Jacobsen I, Baelum J, Carstensen O, Skadhauge LR, Feary J, Cullinan P, Sherson DL., Delayed occupational asthma from epoxy exposure., Occup Med, 2019;69:511-514,10.1093/occmed/kqz088

Keywords: oa, SIC ch, epoxy,cr, amine, isophorone diamine (2); diethyltoluene diamine; 1,3-diamine pentane; 4-methyl-1-piperazine diamine; 4,4,diaminocyclohexyl methane; 4-4 methylenebis(N,N-diglycyl aniline; 1,4-butanediol diglyceryl ether

Known Authors

Paul Cullinan, Royal Brompton Hospital, London, UK Paul Cullinan

Jesper Baelum, Jesper Baelum

Jo Feary, Royal Brompton Hospital Jo Feary

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Abstract

BACKGROUND:
A delayed asthma reaction occurring several hours after exposure is difficult to diagnose.

AIMS:
To confirm a delayed asthma reaction in five workers following epoxy exposure.

CASE REPORT:
Working conditions with exposure to epoxy encountered at the workplace were reproduced in a challenge chamber. Specific inhalation challenge (SIC) with epoxy was compared to a control challenge. All five cases had delayed a asthma response 6-15 h after epoxy exposure.

CONCLUSIONS:
Our study confirms that SIC is a useful tool in diagnosing delayed asthma response.

Full Text

Comments

hardeners are isophorone diamine (2); diethyltoluene diamine; 1,3-diamine pentane; 4-methyl-1-piperazine diamine; 4,4,diaminocyclohexyl methane; 4-4 methylenebis(N,N-diglycyl aniline; 1,4-butanediol diglyceryl ether

2/24/2020

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