Symptomatic adults with normal surveillance spirometry have increased respiratory mortality

Adults with respiratory symptoms and spirometry within normal limits have increased respiratory risks over the next 8 years. This is a follow-up from a Danish population sample showing that adults with respiratory symptoms and normal spirometry are more likely to die, have hospital admissions for pneumonia and airflow obstruction, than adults with similar spirometry and no respiratory symptoms. Their spirometry was lower than those without symptoms but the increased risks remained after adjustment for FEV1. Those with airflow obstruction and no symptoms had the same outcomes as those with normal spirometry and symptoms. Those with both symptoms and airflow obstruction did worst.

References

	Çolak Y, Nordestgaard BG, Vestbo J, Lange P, Afzal S, Prognostic significance of chronic respiratory symptoms in individuals with normal spirometry., Eur Respir J, 2019;:,DOI: 10.1183/13993003.00734-2019

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