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Immediate asthmatic reactions following low molecular weight antigens last longer than those following high molecular weight antigens

Immediate asthmatic reactions following low molecular weight antigens last longer than those following high molecular weight antigens

The time to maximum fall in FEV1 and time to recovery to within 10% of baseline following specific inhalation challenges were both significantly shorter for exposure to high molecular weight agents than low molecular weight agents. This is the first time that these differences have been found, from a large database of challenges in Montreal.

References

Abstract Available for Distinct temporal patterns of immediate asthmatic reactions due to high- and low-molecular-weight agents Malo J-L, Ghezzo H, LArchevêque J, Distinct temporal patterns of immediate asthmatic reactions due to high- and low-molecular-weight agents, Clin Exp Allergy, 2012;42:1021-1027,
Jean-Luc Malo, Hôpital de Sacré Coeur, Montreal, Quebec, Canada, an author of 'Distinct temporal patterns of immediate asthmatic reactions due to high- and low-molecular-weight agents' Heberto Ghezzo, Montreal, an author of 'Distinct temporal patterns of immediate asthmatic reactions due to high- and low-molecular-weight agents'

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