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Mitoxantrone causes occupational asthma in an oncology nurse (new cause)

Mitoxantrone causes occupational asthma in an oncology nurse (new cause)


Agent Mitoxantrone
Job Oncology nurse
Specific IgE not done 
Skin prick test not done
Non-specific reactivity Histamine Pc20 0.093 mg/ml
Serial Peak Flow not done
 BAL increase in eosinophils, netrophils and lymphocytes 6 and 18 hours post challenge
 FENO not done
Specific Challenge 

Specific bronchial challenge showing dual reaction to mitoxantrone. No control in patient, but control in unexposed asthmatic. Method of exposurre not stated

Follow-up

no information

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References

Abstract Available for Occupational asthma due to mitoxantrone Walusiak J, Wittczak T, Ruta U, Palczynsk C, Occupational asthma due to mitoxantrone, Allergy, 2002;57:461,
Jolanta Walusiak, Lodz, an author of 'Occupational asthma due to mitoxantrone'

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