Mitoxantrone causes occupational asthma in an oncology nurse (new cause) |
|
Agent |
Mitoxantrone |
Job |
Oncology nurse |
Specific IgE |
not done |
Skin prick test |
not done |
Non-specific reactivity |
Histamine Pc20 0.093 mg/ml |
Serial Peak Flow |
not done |
BAL |
increase in eosinophils, netrophils and lymphocytes 6 and 18 hours post challenge |
FENO |
not done |
Specific Challenge |
Specific bronchial challenge showing dual reaction to mitoxantrone. No control in patient, but control in unexposed asthmatic. Method of exposurre not stated |
Follow-up |
no information |
References
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