The prognosis after acute irritant-induced asthma is worse than after sensitiser-induced occupational asthma |
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This is the best study of outcome from acute or recurrent irritant exposures at work. The outcome after 6-8 months was worse than with sensitiser-induced occupational asthma, with more treatment and more exacerbations. Those with single and repeated large exposures had similar outcomes. At follow-up 46% were in their original jobs, 16% in modified jobs, 10% unemployed, 19% off sick and 9% with other outcomes.
The identified exposures were mixtures (18), Acids and alkalis (25)Inorganic gasses (6), endotoxin (4) and oxidisers (2)
References
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Lantto J, Suojalehto H, Karvala K, Remes J, Soini S, Suuronen K, Lindström I,
Clinical Characteristics of Irritant-Induced Occupational Asthma,
J Allergy Clin Immunol Pract,
2022;10:1554-1561,https://doi.org/10.1016/j.jaip.2022.02.021
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