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FEV1/FVC can replace FEV1 % predicted when predicted equations unreliable

FEV1/FVC can replace FEV1 % predicted when predicted equations unreliable
The GLI predicted equations for spirometry do not apply to most of the population of South Asia due to substantial variance between different predicted equations. This poses a problem for diseases defined by spirometry, in this case stage 3 byssinosis. The authors show that using the unadjusted FEV1/FVC ratio can overcome this problem with a disease defined in terms of fixed airflow obstruction.

References

Abstract Available for Impact of using different predictive equations on the prevalence of chronic byssinosis in textile workers in Pakistan Nafees AA, Muneer MZ, Matteis SD, Amaral A, Burney P, Cullinan P, Impact of using different predictive equations on the prevalence of chronic byssinosis in textile workers in Pakistan, Occup Environ Med, 2022;79:242-244,http://dx.doi.org/10.1136/oemed-2021-107680
Paul Cullinan, Royal Brompton Hospital, London, UK, an author of 'Impact of using different predictive equations on the prevalence of chronic byssinosis in textile workers in Pakistan' Peter Burney, Kings College, London, an author of 'Impact of using different predictive equations on the prevalence of chronic byssinosis in textile workers in Pakistan'

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