FEV1/FVC can replace FEV1 % predicted when predicted equations unreliable |
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The GLI predicted equations for spirometry do not apply to most of the population of South Asia due to substantial variance between different predicted equations. This poses a problem for diseases defined by spirometry, in this case stage 3 byssinosis. The authors show that using the unadjusted FEV1/FVC ratio can overcome this problem with a disease defined in terms of fixed airflow obstruction.
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