Agent |
Cobalt |
Other Names
|
Hard metal, stellite |
Sources of Exposure
|
Hard metal manufacture and grinding, metal working, metal-working fluid |
Jobs |
Moulder, grinder, sinterer, machinist, |
Epidemiological Studies
|
Sauni R, Linna A, Oksa P, Nordman H, Tuppurainen M, Uitti J, Cobalt asthma — a case series from a cobalt plant, Occup Med, 2010; 60 : 301-306 |
Air Measurements |
working within exposure limits does not prevent occupational asthma |
Specific IgE/ Skin prick test |
Have been described but not generally available. Shirakawa T, Kusaka Y, Morimoto K, Specific IgE antibodies to nickel in workers with known reactivity to cobalt, Clin Exp Allergy, 1992; 22: 213-218 |
Biological Monitoring |
Post shift urine cobalt identifies exposure |
Specific Challenge |
Genenerally nebulised cobalt chloride 0.1-2mg/ml or cobalt dust 0.1-1 ml/l (Occup Med, 2010; 60 : 301-306) |
Early References
|
Jobs H, Ballhausen C., Powder metallurgy as a source of dust from the medical and technical standpoint, Vertrauensartz Krankenkasse, 1940; 8 : 142- Bech AO, Kipling MD, Heather JC, Hard metal disease, Brit J Industr Dis, 1962; 19: 239- Demedts M, Gheysens B, Nagels J, Cobalt lung in diamond polishers, Am Rev Respir Dis, 1984; 130: 130-135 |
Substitutes
|
Metal-working fluids can be formulated to reduce cobalt solubility. |