What are the sensitivity and the specificity of specific IgE testing in the diagnosis of validated cases of occupational asthma?
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**
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2+
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Both skin prick and serological tests are highly sensitive for detecting specific IgE and occupational asthma caused by most high molecular weight agents, but are not specific for diagnosing asthma.
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This statement is in the "Diagnosis of an affected worker"
section of evidence linked statements
Evidence
Baur X, Czuppon A
,
Diagnostic Validation Of Specific Ige Antibody Concentrations, Skin Prick Testing, And Challenge Tests In Chemical Workers With Symptoms Of Sensitivity To Different Anhydrides
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J Allergy Clin Immunol
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1995
;
96
:
489-494
PlattsMills TAE, Longbottom J, Edwards J, Cockcroft A, Wilkins S
,
Occupational asthma and rhinitis related to laboratory rats: serum IgG and IgE antibodies to the rat urinary allergen
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J Allergy Clin Immunol
,
1987
;
79
:
505-515
Vandenplas O, Delwiche JP, Evrard G et al
,
Prevalence of occupational asthma due to latex among hospital personnel
,
Am J Respir Crit Care Med
,
1995
;
151
:
54-60