BOHRF Original Authors' Main Conclusions
The original authors' main conclusions are taken from Abstract, Results and
Discussion. They are decided upon by the authors of the BOHRF occupational
asthma guidelines and form part of the guidelines.
Study aimed to identify risk factors for development of immunologically mediated respiratory disease in workers exposed to hexahydrophthalic anhydride (HHPA). Of 57 employees in a workplace molding operation utilising HHPA, 7 had both IgE- and IgG-mediated disease, whereas 9 had only IgE-mediated disease. Although neither smoking, age, nor race were risk factors for development of immunologically mediated disease, exposure level and specific antibody were. Authors conclude that development of immunologically mediated respiratory disease due to HHPA is most closely associated with exposure level and development of specific IgE or IgG antibodies.
BOHRF Associated Evidence Statements
The BOHRF occupational asthma guidelines state that this reference is associated
with the following evidence statements
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