Reference

Merget R, Schulte A, Gebler A, Breitstadt R, Kulzer R, Berndt ED, Baur, X, SchultzeWerninghaus G, Outcome of occupational asthma due to platinum salts after transferral to low-esposure areas, Int Arch Occup Environ Health, 1999;72:33-39,

BOHRF Original Authors' Main Conclusions

The original authors' main conclusions are taken from Abstract, Results and Discussion. They are decided upon by the authors of the BOHRF occupational asthma guidelines and form part of the guidelines.

83 workers in study: - 9 continued to be exposed (Group A), 16 were transferred within building (Group B), 39 were transferred within plant but different building (Group C) and 19 left the plant (Group D). At median period of about 4 years after diagnosis, asthma symptoms were reported by all subjects still exposed but by only 37/74 after transferral, with no difference being found between groups B, C and D. For the majority of subjects with occupational asthma due to Platinum salts, transfer to low exposure areas may not be associated with a more unfavourable outcome as compared with complete removal from exposure sources.

BOHRF Associated Evidence Statements

The BOHRF occupational asthma guidelines state that this reference is associated with the following evidence statements

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The likelihood of improvement or resolution of symptoms or of preventing deterioration is greater in workers who have no further exposure to the causative agent.

Redeployment to a low exposure area may lead to improvement or resolution of symptoms or prevent deterioration in some workers, but is not always effective.

Non Bohrf Information

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