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Can acute formaldehyde exposure trigger sensitisation to another agent?
I carry our respiratory health surveillance for a poultry hatchery company. One of their workers was acutely exposed to ? formaldehyde in November 2016 enough to prompt an A&E attendance, and subsequently developed respiratory symptoms. Initially these were unrelated to work but at his kast surv ...
Occupational Asthma, Health Professional, 8/18/2018, 8/20/2018,

occupational asthma from chromium
Is it possible to become sensitised (respiratory) to the grindings of a chrome-containing prosthesis; or does the chrome need to be in the form of a hexavalent salt?
Occupational Asthma, Specialist, 8/1/2018, 8/1/2018,

Comments for the page titled: "Gene-environment interactions identified in cleaners and healthcare workers with occupational asthma."
Exposure alone does not account for susceptibility to develop occupational asthma, and gene-environment interactions are likely to be involved (as well as other factors such as smoking and any possible high-dose tolerance). Data from three large European cohorts: EGEA, SAPALDIA, and ECRHS used a ...
Page Comments, , 8/1/2018, 8/1/2018,

Comments for the paper: "Genes Interacting with Occupational Exposures to Low Molecular Weight Agents and Irritants on Adult-Onset Asthma in Three European Studies", 2016, Environ Health Perspect
Exposure alone does not account for susceptibility to develop occupational asthma, and gene-environment interactions are likely to be involved (as well as other factors such as smoking and any possible high-dose tolerance). Data from three large European cohorts: EGEA, SAPALDIA, and ECRHS used a ...
Published Paper Comments, , 8/1/2018, 8/1/2018,

Comments for the paper: "Are high- and low-molecular-weight sensitizing agents associated with different clinical phenotypes of occupational asthma?", 2018, Allergy
This is the first result of a collaboration between centres offering specific inhalation testing in the diagnosis of occupational asthma, and contains data of 544 positive tests with high molecular weight agents and 635 tests with low molecular weight agents. As expected high molecular weight ag ...
Published Paper Comments, , 8/1/2018, 8/1/2018,

1. Is it possible to have undiagnosed asthma if you have confirmed allergies and some family history and 2. Do you think that I could be allergic to bitrex?
I left school and went to work as a Pharmacology Laboratory Technician for over 2O years. I started work in 1987 when processes and procedures were not as good in this area as they are nowadays. My mother and brother are both asthmatics and I knew that I suffered from "hay fever" in the summer ...
Occupational Asthma, Worker, 1/31/2013, 7/18/2018,

Egg & peanut allergy greater predisposition to allergic alveolitis
My son is to start work in a centre for birds and animals. Birds include a few parakeets, pigeons, chickens. He has peanut allergy (can go into shock), and egg allergy (vomits violently). He is also allergic to shellfish, house dust and pollen. (Mild asthma -has inhalers). On the whole his a ...
Oasys, Health Professional, 8/6/2016, 4/29/2018,

Pine oil
What do you consider the minimum latency to pine oil/colophony exposure in a non asthmatic?
Occupational Asthma, Specialist, 1/11/2018, 4/29/2018,

Comments for the paper: "Sensitising effects of genetically modified enzymes used in flavour, fragrance, detergence and pharmaceutical production: cross-sectional study", 2017, Occup Environ Med
Genetically modified enzymes are now present in a wide range of industries and cause sensitisation which often shows little cross-reactivity with the native enzyme, so can be missed unless the genetically modified enzyme is used to testing. Uses include new ?avours and aroma in low-fat food, lip ...
Published Paper Comments, , 4/9/2018, 4/9/2018,

Natural Gas and Tetrahydrothiophene
I am a respiratory physician I have had a two patients claiming exacerbation of asthma as a result of exposure to natural gas leaks within their working environment. Is there any information about this? Could the odourant Tetrahydrothiophene be responsible as there is nearly nothing on toxic ...
Occupational Asthma, Specialist, 3/11/2018, 3/11/2018,

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