Oasys and Occupational Asthma

This website contains information on Occupational Asthma and a free multi award winning computer program called OASYS, which is used to help diagnose Occupational Asthma from serial peak flow records. Oasys shows further information and downloads for the Oasys program. References is a searchable database of more than 5000 published papers in the field of occupational asthma. Causes shows some of the causes of occupational asthma. The Shield scheme reports some statistics for occupational asthma, mainly in the West midlands region, UK. BOHRF shows the evidence based occupational asthma guidelines for the UK. The interactive Case Histories are a learning resource for interested health professionals. There are also Medics, Specialists, Employers and Worker sections.

Latest News

Occupational asthma: Bakers asthma and rhinitis still occuring with exposure levels <1mg,m3 Bakers asthma and rhinitis still occuring with exposure levels <1mg,m3 08 01 2023
Occupational asthma: Metalworking fluid HP with no mycobacteria Metalworking fluid HP with no mycobacteria 08 01 2023
Occupational asthma: Office workers constitute 5% of those with confirmed occupational asthma. Office workers constitute 5% of those with confirmed occupational asthma 06 11 2022
Occupational asthma: Small changes in PEF may be first sign of developing occupational asthma Small changes in PEF may be first sign of developing occupational asthma 06 11 2022
Occupational asthma: Removing the cause improves survival in fibrotic hypersensitivity pneumonitis Removing the cause improves survival in fibrotic hypersensitivity pneumonitis 23 10 2022

Latest Publications

Full Text Available for Job and exposure intensity among hospital cleaning staff adversely affects respiratory health. Ndlela NH, Naidoo RN, Job and exposure intensity among hospital cleaning staff adversely affects respiratory health., Am J Ind Med, 2023;:1-13,doi:10.1002/ajim.23456

Abstract Available for Impact of occupational asthma on health and employment status: a long-term follow-up study Mason P, Liviero F, Paccagnella ER, Biasioli M, Maestrelli P, Frigo AC, Impact of occupational asthma on health and employment status: a long-term follow-up study, Occup Environ Med, 2022;-:-,doi: 10.1136/oemed-2022-108504
Piero Maestrelli, Padova University, Italy, an author of 'Impact of occupational asthma on health and employment status: a long-term follow-up study'

Full Text Available for Workplace-related inhalation test - Specific inhalation challenge: S2k Guideline of the German Society for Occupational and Environmental Medicine e.V. (DGAUM), the German Society for Pneumology and Respiratory Medicine e.V. (DGP) and the German Society for Allergology and Clinical Immunology e.V. (DGAKI). Preisser AM, Koschel D, Merget R, Nowak D, Raulf M, Heidrich J., Workplace-related inhalation test - Specific inhalation challenge: S2k Guideline of the German Society for Occupational and Environmental Medicine e.V. (DGAUM), the German Society for Pneumology and Respiratory Medicine e.V. (DGP) and the German Society for Allergology and Clinical Immunology e.V. (DGAKI)., Allergol Select., 2021;5:315-334,doi: 10.5414/ALX02280E
Dennis Nowak, Institute fur Arbeits, Munich, an author of 'Workplace-related inhalation test - Specific inhalation challenge: S2k Guideline of the German Society for Occupational and Environmental Medicine e.V. (DGAUM), the German Society for Pneumology and Respiratory Medicine e.V. (DGP) and the German Society for Allergology and Clinical Immunology e.V. (DGAKI).' Rolf Merget, Bochum, an author of 'Workplace-related inhalation test - Specific inhalation challenge: S2k Guideline of the German Society for Occupational and Environmental Medicine e.V. (DGAUM), the German Society for Pneumology and Respiratory Medicine e.V. (DGP) and the German Society for Allergology and Clinical Immunology e.V. (DGAKI).' Alexandra Preisser, Hamburg, an author of 'Workplace-related inhalation test - Specific inhalation challenge: S2k Guideline of the German Society for Occupational and Environmental Medicine e.V. (DGAUM), the German Society for Pneumology and Respiratory Medicine e.V. (DGP) and the German Society for Allergology and Clinical Immunology e.V. (DGAKI).'

Go to "References" section.

Latest Forum Questions

Comments for the paper: "Impact of occupational asthma on health and employment status: a long-term follow-up study", 2022, Occup Environ Med
The numbers with continuing employment after diagnosis by SIC is higher than many previous studies, despite the lack of emphasis on this by Italian compensation authorities. There is no information as to how this was achieved. Nearly 80% were still employed at follow-up, most changing their place of work, which was associated with more recovery than those relocated in their original workplace. There was no overall improvement in FEV1 % predicted at follow-up, but some improvement in NSBR and FeNO. This paper has a low follow-up rate (60/204) and finds similar factors relating to poorer prognosis as earlier studies (lower presenting FEV1 and NSBR, longer time exposed after symptoms started, longer latent interval).
Published Paper Comments, , 1/12/2023, 1/12/2023,

Comments for the paper: "Workplace-related inhalation test - Specific inhalation challenge: S2k Guideline of the German Society for Occupational and Environmental Medicine e.V. (DGAUM), the German Soc
These are practical guidelines for occupational challenge testing in Germany, and do not attempt to be evidence-based. They include indications and methods, but omit the need for a control exposure for most patients. The reasons for this are more pragmatic than evidence-based. They are perhaps more appropriate for countries who require a positive SIC for compensation, the tests often carried out after a decision to remove the worker from exposure has been made.
Published Paper Comments, , 1/9/2023, 1/9/2023,

Comments for the paper: "Flour exposure, sensitization and respiratory health among Alberta trainee bakers", 2022, Occup Med
Bread is one of the few things that is made very differently in wheat growing areas of the world, varying from mass production with genetically engineered enzymes to artisan baking with natural products using many different types of grain and baking processes. The current study is from Alberta, Canada, where artisan baking is common. The study identifies new sensitisation to flour with average exposure levels around 500ug/m3. The paper identified many of the problems in performing longitudinal cohort studies including identifying participants before (or very soon after) first exposure, maintaining contact with them in sparsely populated areas, standardising skin prick testing and obtaining relevant skin-testing enzymes.
Published Paper Comments, , 1/8/2023, 1/8/2023,

The Website

This website is run by the Oasys research group, part of the Midland Thoracic Society, UK. We are an independent group of clinicians and researchers, and run a clinical service for workers with occupational lung disease as part of the British National Health Service. We have developed the Oasys program to help ourselves and others in the diagnosis of occupational asthma. We have no specific funding, relying on research grants and the enthusiasm of our group. The website is written by Cedd Burge, who receives some funding from the group. The group meets every Friday evening after the occupational lung disease clinic, as shown below.



As a casual user of this site (without logging in or registering) you can view all the information and use all the contact pages. Registered and logged in users (registering is free and we won't abuse your email) can download and use the Oasys program, ask and reply to questions in the forums, leave comments, add new references, add abstracts and full text links to existing references, answer questions in the case histories and provide evidence and suggest questions for future evidence based guidelines.

If you would like to be added to the list of known authors or collaborators then please register with the website (if you have not already done so) and then get in touch from the contact page. Once we have set the page up you will be able to edit it yourself and indicate which references you have written. Your picture will then be displayed along with each of these references. If you are already in these lists and would like to edit your page then please register with the website and then get in touch from the contact page.

Funding

Recent research grants / contracts have been received from the following.

The Oasys Team

Wasif Anees, Oasys Anees, Wasif (Oasys)
John Belcher, Oasys Belcher, John (Oasys)
Phil Bright, Oasys Bright, Phil (Oasys)
Cedd Burge, Oasys Burge, Cedd (Oasys)
Geraldine Burge, Birmingham Heartlands Hospital Burge, Geraldine (Birmingham Heartlands Hospital)
Sherwood Burge, Oasys Burge, Sherwood (Oasys)
Celia Catton, Oasys Catton, Celia (Oasys)
Vicki Drought, Oasys Drought, Vicki (Oasys)
Angela Evans, ARTP Evans, Angela (ARTP)
Paul Gannon, Dupont Gannon, Paul (Dupont)
Mike Hendy, Oasys Hendy, Mike (Oasys)
Chris Huntley, University Hospitals Birmingham Huntley, Chris (University Hospitals Birmingham)
John Jackson, Jackson Hocking Limited, UK Jackson, John (Jackson Hocking Limited, UK)
Sarah Manney, Birmingham Heartlands Hospital Manney, Sarah (Birmingham Heartlands Hospital)
Jennifer McCoach (now Croft), Oasys McCoach (now Croft), Jennifer (Oasys)
Emmet McGrath, Oasys McGrath, Emmet (Oasys)
David Miedinger, Lucern, Basel and Montreal Miedinger, David (Lucern, Basel and Montreal)
Vicky Moore, Oasys Moore, Vicky (Oasys)
Darren Newton, Oasys Newton, Darren (Oasys)
Charles Pantin, Keele, UK Pantin, Charles (Keele, UK)
Edward Parkes, Birmingham Heartlands Hospital Parkes, Edward (Birmingham Heartlands Hospital)
Alastair Robertson, Selly Oak Hospital Robertson, Alastair (Selly Oak Hospital)
Arun Dev Vellore, Oasys Vellore, Arun Dev (Oasys)
Gareth Walters, Heartlands Walters, Gareth (Heartlands)
David Weir, North Manchester Hospital Weir, David (North Manchester Hospital)

Collaborators

Piero Maestrelli, Padova University, Italy Maestrelli, Piero (Padova University, Italy)
Dennis Nowak, Institute fur Arbeits, Munich Nowak, Dennis (Institute fur Arbeits, Munich)
Jeremy Beach, University of Alberta Beach, Jeremy (University of Alberta)
Katja Radon, Ludwig Maximillian University, Munich Radon, Katja (Ludwig Maximillian University, Munich)
Josep Antó, Barcelona, Catalonia, Spain Antó, Josep (Barcelona, Catalonia, Spain)
Melanie Carder, COEH Manchester Carder, Melanie (COEH Manchester)
Jo Feary, Royal Brompton Hospital Feary, Jo (Royal Brompton Hospital)
Ruth Wiggans, Manchester University Wiggans, Ruth (Manchester University)
Ben Nemery, Leuven, Belgium Nemery, Ben (Leuven, Belgium)
Hille Suojalehto, Finnish Institute of Occupational Health Suojalehto, Hille (Finnish Institute of Occupational Health)

Known Authors

Rolf Merget, Bochum Merget, Rolf (Bochum)
Alexandra Preisser, Hamburg Preisser, Alexandra (Hamburg)
Nicola Cherry, University of Alberta, Edmonton, Canada Cherry, Nicola (University of Alberta, Edmonton, Canada)
Xavier Munoz, Barcelona Munoz, Xavier (Barcelona)
Maria Jesus Cruz, Barcelona Cruz, Maria Jesus (Barcelona)
Laurens de Sadeleer, University Hospitals Leuven, Leuven B-3000, Belgium de Sadeleer, Laurens (University Hospitals Leuven, Leuven B-3000, Belgium)
Martie van Tongeren, Manchester University van Tongeren, Martie (Manchester University)
Martin Seed, Manchester University Seed, Martin (Manchester University)
Steven Ronsman, Leuven Ronsman, Steven (Leuven)
de Sadeleer Laurens, Leuven Laurens, de Sadeleer (Leuven)

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