Oasys and Occupational Asthma

This website contains information on Occupational Asthma and a free multi award winning computer program called OASYS, which is used to help diagnose Occupational Asthma from serial peak flow records. Oasys shows further information and downloads for the Oasys program. References is a searchable database of more than 5000 published papers in the field of occupational asthma. Causes shows some of the causes of occupational asthma. The Shield scheme reports some statistics for occupational asthma, mainly in the West midlands region, UK. BOHRF shows the evidence based occupational asthma guidelines for the UK. The interactive Case Histories are a learning resource for interested health professionals. There are also Medics, Specialists, Employers and Worker sections.

Latest News

Occupational asthma: Can type IV hypersensitivity cause occupational asthma? Can type IV hypersensitivity cause occupational asthma? 29 06 2022
Occupational asthma: The prognosis after acute irritant-induced asthma is worse than after sensitiser-induced occupational asthma The prognosis after acute irritant-induced asthma is worse than after sensitiser-induced occupational asthm 28 06 2022
Occupational asthma: Cannabis allergy confirmed by positive skin prick tests using crushed cannabis leaves in normal saline Cannabis allergy confirmed by positive skin prick tests using crushed cannabis leaves in normal saline 18 06 2022
Occupational asthma: FEV1/FVC can replace FEV1 % predicted when predicted equations unreliable FEV1/FVC can replace FEV1 % predicted when predicted equations unreliable 14 04 2022
Occupational asthma: Genes separate fibrotic from non-fibrotic HP Genes separate fibrotic from non-fibrotic HP 13 04 2022

Latest Publications

Full Text Available for Prenatal occupational disinfectant exposure and childhood allergies: the Japan Environment and Children's study Kojima R, Shinohara R, Kushima M, Horiuchi S, Otawa S, Yokomichi H, Akiyama Y, Ooka T, Miyake K, Yamagata , Prenatal occupational disinfectant exposure and childhood allergies: the Japan Environment and Children's study, Occup Environ Med, 2022;79:521-526,10.1136/oemed-2021-108034

Full Text Available for Are aerosols generated during lung function testing in patients and healthy volunteers? Results from the AERATOR study Sheikh S, Hamilton FW, Nava GW, Gregson FKA, Arnold DT, Riley C, Brown J, Reid JP, Bzdek BR, Maskell NA, Dodd JW, Are aerosols generated during lung function testing in patients and healthy volunteers? Results from the AERATOR study, Thorax, 2022;77:292-294,. doi:10.1136/thoraxjnl-2021-217671

Abstract Available for Aerosol generation during pulmonary function testing: Monitoring during different testing modalities Wu JKY, Ryan M, Hiebert RJ, Han Z, Liu A, Jeong C-H, Mubareka S, Evans GJ, Chow C-W, Aerosol generation during pulmonary function testing: Monitoring during different testing modalities, Canadian Journal of Respiratory, Critical Care, and Sleep Medicine, 2021;:1965926,doi: 10.1080/24745332.2021.1965926

Go to "References" section.

Latest Forum Questions

1. Is it possible to have undiagnosed asthma if you have confirmed allergies and some family history and 2. Do you think that I could be allergic to bitrex?
I left school and went to work as a Pharmacology Laboratory Technician for over 2O years. I started work in 1987 when processes and procedures were not as good in this area as they are nowadays. My mother and brother are both asthmatics and I knew that I suffered from "hay fever" in the summer with runny eyes and sneezing. (Though I don't seem to have hay fever nowadays!). I have never been diagnosed with asthma, but after some time working (I really can't remember when this would have been now), I began to suspect that I was becoming allergic to animals at my work and via my GP, it was confirmed with skin prick tests that I was allergic to almost, if not all the animal species that I came into contact with. I was able to manage this reasonably well with various control measures (batter powered full face hood, nitrile gloves, annual lung function tests etc.) and as processes improved over the years, I didn't suffer too much because of it. I changed jobs four years ago and am now mainly office based. However, recently I experienced what I consider to be a delayed hypersensitive allergic/irritant skin reaction (urticaria) approximately 48hrs after a training session to be a qualitative face-fit tester. I believe that I may be one of the very few numbers of people that may be hypersensitive to bitrex (denatonium benzoate). There is so little research in this area, but there are sporadic reports of adverse respiratory and skin reactions in primarily the healthcare sector. Given my family history, my known allergies to animals and my known exposure to a fairly large number of substances over the years (including related bitrex-like subtances of local anesthetics such as lignocaine, xylocaine, procaine), could anyone give me their thoughts on my questions above and how I convince my OH Dept. that I think I do warrant an allergy text to this substance, to rule it in or out one way or another? Many thanks
Occupational Asthma, Worker, 1/31/2013, 7/25/2022,

Comments for the paper: "Associations of multiple metals with lung function in welders by four statistical models", 2022, Chemosphere
Can someone explain the stats used in this paper?
Published Paper Comments, , 7/4/2022, 7/4/2022,

Comments for the paper: "Associations of multiple metals with lung function in welders by four statistical models", 2022, Chemosphere
Can someone explain the stats used in this paper?
Published Paper Comments, , 7/4/2022, 7/4/2022,

The Website

This website is run by the Oasys research group, part of the Midland Thoracic Society, UK. We are an independent group of clinicians and researchers, and run a clinical service for workers with occupational lung disease as part of the British National Health Service. We have developed the Oasys program to help ourselves and others in the diagnosis of occupational asthma. We have no specific funding, relying on research grants and the enthusiasm of our group. The website is written by Cedd Burge, who receives some funding from the group. The group meets every Friday evening after the occupational lung disease clinic, as shown below.



As a casual user of this site (without logging in or registering) you can view all the information and use all the contact pages. Registered and logged in users (registering is free and we won't abuse your email) can download and use the Oasys program, ask and reply to questions in the forums, leave comments, add new references, add abstracts and full text links to existing references, answer questions in the case histories and provide evidence and suggest questions for future evidence based guidelines.

If you would like to be added to the list of known authors or collaborators then please register with the website (if you have not already done so) and then get in touch from the contact page. Once we have set the page up you will be able to edit it yourself and indicate which references you have written. Your picture will then be displayed along with each of these references. If you are already in these lists and would like to edit your page then please register with the website and then get in touch from the contact page.

Funding

Recent research grants / contracts have been received from the following.

The Oasys Team

Wasif Anees, Oasys Anees, Wasif (Oasys)
John Belcher, Oasys Belcher, John (Oasys)
Phil Bright, Oasys Bright, Phil (Oasys)
Cedd Burge, Oasys Burge, Cedd (Oasys)
Geraldine Burge, Birmingham Heartlands Hospital Burge, Geraldine (Birmingham Heartlands Hospital)
Sherwood Burge, Oasys Burge, Sherwood (Oasys)
Celia Catton, Oasys Catton, Celia (Oasys)
Vicki Drought, Oasys Drought, Vicki (Oasys)
Angela Evans, ARTP Evans, Angela (ARTP)
Paul Gannon, Dupont Gannon, Paul (Dupont)
Mike Hendy, Oasys Hendy, Mike (Oasys)
Chris Huntley, University Hospitals Birmingham Huntley, Chris (University Hospitals Birmingham)
John Jackson, Jackson Hocking Limited, UK Jackson, John (Jackson Hocking Limited, UK)
Sarah Manney, Birmingham Heartlands Hospital Manney, Sarah (Birmingham Heartlands Hospital)
Jennifer McCoach (now Croft), Oasys McCoach (now Croft), Jennifer (Oasys)
Emmet McGrath, Oasys McGrath, Emmet (Oasys)
David Miedinger, Lucern, Basel and Montreal Miedinger, David (Lucern, Basel and Montreal)
Vicky Moore, Oasys Moore, Vicky (Oasys)
Darren Newton, Oasys Newton, Darren (Oasys)
Charles Pantin, Keele, UK Pantin, Charles (Keele, UK)
Edward Parkes, Birmingham Heartlands Hospital Parkes, Edward (Birmingham Heartlands Hospital)
Alastair Robertson, Selly Oak Hospital Robertson, Alastair (Selly Oak Hospital)
Arun Dev Vellore, Oasys Vellore, Arun Dev (Oasys)
Gareth Walters, Heartlands Walters, Gareth (Heartlands)
David Weir, North Manchester Hospital Weir, David (North Manchester Hospital)

Collaborators

Ruth Wiggans, Manchester University Wiggans, Ruth (Manchester University)
Ben Nemery, Leuven, Belgium Nemery, Ben (Leuven, Belgium)
Hille Suojalehto, Finnish Institute of Occupational Health Suojalehto, Hille (Finnish Institute of Occupational Health)
Irmeli Lindstrom, Finnish Institute of Occupational Health Lindstrom, Irmeli (Finnish Institute of Occupational Health)
Melanie Carder, COEH Manchester Carder, Melanie (COEH Manchester)
David Fishwick, Royal Hallamshire Hospital, Sheffield, UK Fishwick, David (Royal Hallamshire Hospital, Sheffield, UK)
Jennifer Canizales, Royal Brompton Hospital Canizales, Jennifer (Royal Brompton Hospital)
Neeraj Gupta, Maulana Azad Medical College, Delhi Gupta, Neeraj (Maulana Azad Medical College, Delhi)
Paul Cullinan, Royal Brompton Hospital, London, UK Cullinan, Paul (Royal Brompton Hospital, London, UK)
Jennifer Hoyle, North Manchester General Hospital Hoyle, Jennifer (North Manchester General Hospital)

Known Authors

Steven Ronsman, Leuven Ronsman, Steven (Leuven)
de Sadeleer Laurens, Leuven Laurens, de Sadeleer (Leuven)
Mohammed Jeebhay, Cape Town Jeebhay, Mohammed (Cape Town)
Bill Glass, Christchurch, New Zealand Glass, Bill (Christchurch, New Zealand)
Jeroen Douwes, Massey University, Wellington, NZ Douwes, Jeroen (Massey University, Wellington, NZ)
Torben Sigsgaard, University of Aarhus Sigsgaard, Torben (University of Aarhus)
Oyvind Omland, Aahus Denmark Omland, Oyvind (Aahus Denmark)
Peter Burney, Kings College, London Burney, Peter (Kings College, London)
Susan Tarlo, Toronto Tarlo, Susan (Toronto)
Moira Chan-Yeung, University of Hong Kong Chan-Yeung, Moira (University of Hong Kong)

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