Occupational Asthma Reference
|
Lavaud F, Bonniaud P, Dalphin JC, Leroyer C, Muller D, Tannous R, Mangiapan G, De Blay F,
Usefulness of omalizumab in ten patients with severe occupational asthma,
Allergy,
2013;68:813-815,
|
|
|
Keywords: omalizumab, treatment, occupational asthma, France, wheat, cat, flour, isocyanate, acrylate, tetrachloroethylene, baker, vet, farmer, painter, dry cleaner,
Known Authors
If you would like to become a known author and have your picture displayed along with your papers then please get in touch from the contact page. Known authors can choose to receive emails when their papers receive comments.
Abstract
Background
The management of severe occupational asthma (OA) remains problematic and new alternative treatments providing better disease control are required, ideally enabling affected individuals to remain in their job.
Methods
Ten patients with severe uncontrolled OA were treated with the monoclonal anti-IgE antibody omalizumab. In six cases the causative agent was a high molecular weight (HMW) compound and in four cases it was a low molecular weight (LMW) chemical. All of the patients had well documented OA despite workplace adjustments.
Results
During treatment, nine patients exhibited a lower rate of asthma exacerbations and used less oral or inhaled corticosteroids. Seven patients were able to continue working at the same workplace as before treatment.
Conclusion
We have demonstrated that omalizumab is a potential treatment for severe uncontrolled OA and enabled seven of the ten patients in the study to remain in their job.
Full Text
Full text of this reference not available
Please Log In or Register to add the full text to this reference
Comments
|
No resonse in the rubber worker exposed to acrylates, , optimal control in 2/2 bakers, 1/2 farmers and 1/2 vets
|
Please sign in or register to add your thoughts.