Occupational Asthma Reference

Merget R, Sander I, van Kampen V, Raulf-Heimsoth M, Ulmer H, Kulzer R, Bruening T, Occupational immediate-type asthma and rhinitis due to rhodium salts, Am J Ind Med, 2010;53:42-46,

Keywords: new cause, germany, rhodium, electroplater, rhinitis, occupational asthma, case report, skin prick test, challenge, platinum

Known Authors

Rolf Merget, Bochum Rolf Merget

Monika Raulf-Heimsoth, Bochum Monika Raulf-Heimsoth

If you would like to become a known author and have your picture displayed along with your papers then please get in touch from the contact page. Known authors can choose to receive emails when their papers receive comments.

Abstract

Background
Whereas platinum salts are well known occupational allergens, rhodium salts have not been identified as inhalative sensitizing substances.

Methods
A 27-year-old atopic operator of an electroplating plant developed work-related shortness of breath and runny nose with sneezing after exposure to rhodium salts. Quantitative skin prick tests (SPT) and bronchial challenge tests with a dosimeter protocol were performed with quadrupling doses of the sodium chloride salts of rhodium (Na3RhCl6) and platinum (Na2PtCl6).

Results
The patient showed positive SPT reactions and positive bronchial immediate-type reactions with rhodium and platinum salts. Sensitivity to rhodium salt was much higher than to platinum salt; the molar concentrations differed by a factor of 256 in SPT and a factor of 16 in bronchial challenges.

Conclusions
Rhodium salts should be considered as occupational immediate-type allergens.

Full Text

Full text of this reference not available

Please Log In or Register to add the full text to this reference

Associated Questions

There are no associations for this paper.

Please Log In or Register to put forward this reference as evidence to a question.

Comments

Please sign in or register to add your thoughts.


Oasys and occupational asthma smoke logo