Occupational Asthma Reference

Algranti E, Mendonça EMC, Ali SA, Kokron CM, Occupational asthma caused by Ipe (Tabebuia spp) dust, J Inv Allergod Clin Immunol, 2005;15:81-83,
(Plain text: Algranti E, Mendonca EMC, Ali SA, Kokron CM, Occupational asthma caused by Ipe (Tabebuia spp) dust, J Inv Allergod Clin Immunol)

Keywords: Occupational asthma, Ipe, (Tabebuia spp), new cause, Brazil, challenge, wood, prick test positive, carpenter

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Ipe is a resistant hardwood that contains naphtoquinones. It is easily found and frequently used in South and Central America. Naphtoquinones are skin sensitizers.

To describe a case of occupational asthma related to Ipe wood dust.

The patient was submitted to a clinical evaluation consisting of a respiratory symptom questionnaire,occupational history, serial measurements of lung function by spirometry, skin prick tests, patch tests, specific IgE and specific bronchial provocation tests to Ipe dust.

Serial lung function measurements showed sustained regression of obstruction following removal from exposure. Skin prick tests, but not patch tests, were positive to Ipe, and a specific bronchial challenge showed a late asthmatic reaction. Specific IgE search was negative.

Exposure to Ipe wood dust can lead to occupational asthma. The underlying mechanism should be investigated.

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