Occupational Asthma Reference

Algranti E, Mendonça EMC, Ali SA, Kokron CM, Occupational asthma caused by Ipe (Tabebuia spp) dust, J Inv Allergod Clin Immunol, 2005;15:81-83,
(Plain text: Algranti E, Mendonca EMC, Ali SA, Kokron CM, Occupational asthma caused by Ipe (Tabebuia spp) dust, J Inv Allergod Clin Immunol)

Keywords: Occupational asthma, Ipe, (Tabebuia spp), new cause, Brazil, challenge, wood, prick test positive, carpenter

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Abstract

Background:
Ipe is a resistant hardwood that contains naphtoquinones. It is easily found and frequently used in South and Central America. Naphtoquinones are skin sensitizers.

Objective:
To describe a case of occupational asthma related to Ipe wood dust.

Methods:
The patient was submitted to a clinical evaluation consisting of a respiratory symptom questionnaire,occupational history, serial measurements of lung function by spirometry, skin prick tests, patch tests, specific IgE and specific bronchial provocation tests to Ipe dust.

Results:
Serial lung function measurements showed sustained regression of obstruction following removal from exposure. Skin prick tests, but not patch tests, were positive to Ipe, and a specific bronchial challenge showed a late asthmatic reaction. Specific IgE search was negative.

Conclusions:
Exposure to Ipe wood dust can lead to occupational asthma. The underlying mechanism should be investigated.

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