Occupational Asthma Reference

Lietzén R, Virtanen P, Kivimäki M, Sillanmäkif L, Vahtera J, Koskenvuof M, Stressful life events and the onset of asthma, Eur Respir J, 2011;37:1360-1365,
(Plain text: Lietzen R, Virtanen P, Kivimaki M, Sillanmakif L, Vahtera J, Koskenvuof M, Stressful life events and the onset of asthma, Eur Respir J)

Keywords: stress, conflict at work, finland, asthma, incidence,

Known Authors

If you would like to become a known author and have your picture displayed along with your papers then please get in touch from the contact page. Known authors can choose to receive emails when their papers receive comments.

Abstract

The status of stressful life events as a risk factor for asthma is unclear and may be dependent on pre-existing allergic rhinitis. This study examined whether exposure to stressful life events predicted the onset of asthma in adults.

This is a prospective, population-based cohort study of 16,881 males and females, aged 20–54 yrs and free of diagnosed asthma at the beginning of the follow-up (January 1, 2004). Data about stressful life events were gathered with a postal survey. The onset of asthma was ascertained through national registers until December 31, 2005.

During the follow-up period, 192 incident cases of asthma were identified. High total exposure to stressful life events, as indicated by a cumulative severity score, predicted the onset of asthma (hazard ratio 1.96, 95% CI 1.22–3.13). This association was robust to adjustment for demographics, smoking and having a cat/dog at home and it was observed both among those with and without allergic rhinitis at baseline. Of the 10 most stressful life events, the illness of a family member, marital problems, divorce or separation and conflicts with a supervisor were associated with the onset of asthma.

Our study suggests that stressful life events may increase the onset of asthma.

Plain text: The status of stressful life events as a risk factor for asthma is unclear and may be dependent on pre-existing allergic rhinitis. This study examined whether exposure to stressful life events predicted the onset of asthma in adults. This is a prospective, population-based cohort study of 16,881 males and females, aged 20-54 yrs and free of diagnosed asthma at the beginning of the follow-up (January 1, 2004). Data about stressful life events were gathered with a postal survey. The onset of asthma was ascertained through national registers until December 31, 2005. During the follow-up period, 192 incident cases of asthma were identified. High total exposure to stressful life events, as indicated by a cumulative severity score, predicted the onset of asthma (hazard ratio 1.96, 95% CI 1.22-3.13). This association was robust to adjustment for demographics, smoking and having a cat/dog at home and it was observed both among those with and without allergic rhinitis at baseline. Of the 10 most stressful life events, the illness of a family member, marital problems, divorce or separation and conflicts with a supervisor were associated with the onset of asthma. Our study suggests that stressful life events may increase the onset of asthma.

Full Text

Full text of this reference not available

Please Log In or Register to add the full text to this reference

Associated Questions

Registered users of this website have associated this reference with the following questions. This association is not a part of the BOHRF occupational asthma guidelines.

Which agents cause occupational asthma and which workers are at risk?
burgeps This prospective study in Finland finds that severe conflict with a supervisor at work is associated with new onset asthma within the 2 years after the stress was identified by questionnaire. The hazard ratio was about 1.61 similar to divorce or separation (1.65) or a major increase in marital problems (1.62), and more than dealth of a father or mother or violence. The life stressors were additive. This is the best evidence that stress at work might cause asthma.

Please Log In or Register to put forward this reference as evidence to a question.

Comments

Please sign in or register to add your thoughts.


Oasys and occupational asthma smoke logo