Occupational Asthma Reference

Quirce S, Lemière C, de Blay F, del Pozo V, Gerth Van Wijk R, Maestrelli P, Pauli G, Pignatti P, Raulf-Heimsoth M, Sastre J, Storaas T, Moscato G. G, Noninvasive methods for assessment of airway inflammation in occupational settings, Allergy, 2010;65:445-458,
(Plain text: Quirce S, Lemiere C, de Blay F, del Pozo V, Gerth Van Wijk R, Maestrelli P, Pauli G, Pignatti P, Raulf-Heimsoth M, Sastre J, Storaas T, Moscato G. G, Noninvasive methods for assessment of airway inflammation in occupational settings, Allergy)

Keywords: review, asthma • eosinophils • exhaled breath condensate • fractional exhaled nitric oxide • induced sputum • occupational respiratory diseases • rhinitis
Plain text: review, asthma * eosinophils * exhaled breath condensate * fractional exhaled nitric oxide * induced sputum * occupational respiratory diseases * rhinitis

Known Authors

Frederic de Blay, Hopital Universitaires de Strasbourg Frederic de Blay

Joaquin Sastre, Fundacion Jimenez Diaz, Madrid Joaquin Sastre

Piero Maestrelli, Padova University, Italy Piero Maestrelli

Gabrielle Pauli, University of Strasbourg Gabrielle Pauli

Catherine Lemière, Hôpital de Sacré Coeur, Montreal, Quebec, Canada Catherine Lemière

Giana Moscato, Fondazione Salvatore Maugeri, Pavia Giana Moscato

Santiago Quirce, Madrid Santiago Quirce

Monika Raulf-Heimsoth, Bochum Monika Raulf-Heimsoth

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Abstract

The present document is a consensus statement reached by a panel of experts on noninvasive methods for assessment of airway inflammation in the investigation of occupational respiratory diseases, such as occupational rhinitis, occupational asthma, and nonasthmatic eosinophilic bronchitis. Both the upper and the lower airway inflammation have been reviewed and appraised reinforcing the concept of 'united airway disease' in the occupational settings. The most widely used noninvasive methods to assess bronchial inflammation are covered: induced sputum, fractional exhaled nitric oxide (FeNO) concentration, and exhaled breath condensate. Nasal inflammation may be assessed by noninvasive approaches such as nasal cytology and nasal lavage, which provide information on different aspects of inflammatory processes (cellular vs mediators). Key messages and suggestions on the use of noninvasive methods for assessment of airway inflammation in the investigation and diagnosis of occupational airway diseases are issued.

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Comments

not systematic or evidence based
4/2/2010

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