Occupational Asthma Reference

Hong CS, Oh SE, Lee HC, Huh KB, Lee SY, Occupational asthma caused by nickel and zinc, Korean J Intern Med, 1986;1:259-262,

Keywords: occupational asthma, asthma, nickel, zinc, ch, pt, electroplater, cr

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Abstract

A 28-year-old man developed asthma 10 years after working in a metal-plating factory. Recordings of peak expiratory flow rates showed increased variations after exposure at work. Allergy prick skin tests elicited an immediate reaction with nickel sulfate at a concentration of 1 and 10 mg/ml, and with zinc sulfate at a concentration of 10 mg/ml. Inhalation challenges with nickel sulfate and zinc sulfate produced bronchial obstructions. Thus, we concluded that this was a case of asthma caused by nickel sulfate and zinc sulfate

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