Occupational Asthma Reference

White IR, Stewart JR, Rycroft RJ, Allergic contact dermatitis from an organic di-isocyanate, Contact Dermatitis, 1983;9:300-303,

Keywords: dermatitis, polyurethane, HDI

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Abstract

Organic di-isocyanates are used widely in industry. The concomitant respiratory complications are well-known. Cutaneous problems precipitated by skin contact with these chemicals are less well recognised. Allergic contact dermatitis caused by exposure to di-cyclohexylmethane 4,4'-di-isocyanate has been demonstrated in a factory where it was used to form a surface-coating polyurethane. Attention to hygiene methods may have reduced the incidence of cases

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