Occupational Asthma Reference

Nicholson PJ, Cullinan P, Newman Taylor AJ, Burge PS, Boyle C, Evidence based guidelines for the prevention, identification, and management of occupational asthma, Occup Environ Med, 2005;62:290-299,

Keywords: guidelines, prevention, management, occupational asthma, asthma, BOHRF

Known Authors

Paul Cullinan, Royal Brompton Hospital, London, UK Paul Cullinan

Sherwood Burge, Oasys Sherwood Burge

Tony Newman Taylor, Royal Brompton Hospital, London Tony Newman Taylor

Paul Nicholson, Procter And Gamble Occupational Health Paul Nicholson

Catherine Boyle, Health and Safety Executive, UK Catherine Boyle

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Abstract

BACKGROUND
Occupational asthma is the most frequently reported work related respiratory disease in many countries. This work was commissioned by the British Occupational Health Research Foundation to assist the Health and Safety Executive in achieving its target of reducing the incidence of occupational asthma in Great Britain by 30% by 2010.

AIM
The guidelines aim to improve the prevention, identification, and management of occupational asthma by providing evidence based recommendations on which future practice can be based.

METHODS
The literature was searched systematically using Medline and Embase for articles published in all languages up to the end of June 2004. Evidence based statements and recommendations were graded according to the Royal College of General Practitioner's star system and the revised Scottish Intercollegiate Guidelines Network grading system.

RESULTS
A total of 474 original studies were selected for appraisal from over 2500 abstracts. The systematic review produced 52 graded evidence statements and 22 recommendations based on 223 studies.

DISCUSSION
Evidence based guidelines have become benchmarks for practice in healthcare and the process used to prepare them is well established. This evidence review and its recommendations focus on interventions and outcomes to provide a robust approach to the prevention, identification, and management of occupational asthma, based on and using the best available medical evidence. The most important action to prevent cases of occupational asthma is to reduce exposure at source. Thereafter surveillance should be performed for the early identification of symptoms, including occupational rhinitis, with additional functional and immunological tests where appropriate. Effective management of workers suspected to have occupational asthma involves the identification and investigation of symptoms suggestive of asthma immediately they occur. Those workers who are confirmed to have occupational asthma should be advised to avoid further exposure completely and early in the course of their disease to offer the best chance of recovery.

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