Occupational Asthma Reference

Perrin B, Malo JL, Cartier A, Evans S, Dolovich J, Occupational asthma in a pharmaceutical worker exposed to hydralazine, Thorax, 1990;45:980-981,

Keywords: as , pharmaceutical, hydralazine, nc, ch, lr, br, IgE-, IgG-, case report, oa

Known Authors

André Cartier, Hôpital de Sacré Coeur, Montreal, Quebec, Canada André Cartier

Jean-Luc Malo, Hôpital de Sacré Coeur, Montreal, Quebec, Canada Jean-Luc Malo

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Abstract

A pharmaceutical worker developed asthma when exposed to hydralazine, an antihypertensive drug. The diagnosis of occupational asthma was supported by specific inhalation challenges, which produced a late asthmatic reaction and an increase in bronchial responsiveness. No evidence of an IgE or an IgG dependent mechanism could be found.

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