Occupational Asthma Reference

Panzani R, Johansson SGO, Results of skin test and RAST in allergy to a clinically potent allergen (castor bean), Clin Allergy, 1986;16:259-266,

Keywords: oa, IgE, pt, castor bean

Known Authors

If you would like to become a known author and have your picture displayed along with your papers then please get in touch from the contact page. Known authors can choose to receive emails when their papers receive comments.


In order to investigate once more the usefulness of the RAST procedure in the diagnosis of reaginic hypersensitivity, we studied a series of patients showing a well known sensitivity to castor bean, which is a potent antigen, and compared the results with those given by patients with no clinical allergy to this antigen as confirmed by negative skin testing. The latter group included patients with no contact, a remote contact or a close contact with castor bean. Castor bean allergy seems to be a good model in the testing of human reaginic hypersensitivity. We observed in the castor bean positive group of forty-one patients a 95% correlation between RAST positivity and skin test positivity with only two negative RAST scores, and in the castor bean negative group of ninety-four patients, a 97% correlation, with three RAST positive scores. For its specificity and its good sensibility (although lesser than skin testing), RAST can thus be recommended as a diagnostic tool as a complement to skin testing. Moreover, for potent allergens, RAST offers a risk-free diagnostic alternative.

Full Text

Full text of this reference not available

Please Log In or Register to add the full text to this reference

Associated Questions

There are no associations for this paper.

Please Log In or Register to put forward this reference as evidence to a question.


Please sign in or register to add your thoughts.

Oasys and occupational asthma smoke logo