Occupational Asthma Reference

Suresh K, Belchis D, Askin F, Pearse DB, Terry PB., Occupational Asthma Due to Inhalation of Aerosolized Lipophilic Coating Materials., Lung, 2016;194:787-78,10.1007/s00408-016-9919-7

Keywords: OA, Aerospace, histology, BAL, eosinophilia 47%, cardboard box glue,

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We present a case of onset of severe asthma in a 59-year-old patient who worked in an aerospace plant. He was noted to have wheezing on exam and obstruction on PFTs. Review of his occupational history revealed exposure to lipophilic industrial compounds. We outline the radiographic and histologic findings that were found in the patient, and discuss occupational asthma due to inhalation of lipophilic compounds.
DOI 10.1007/s00408-016-9919-7

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Associated Questions

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Which agents cause occupational asthma and which workers are at risk?
burgeps This is a case report of a non-smoking gluer of cardboard boxes in an airospace factory with a history suggestive of occupational asthma and improved spirometry after leaving (no PEF's or challenge). I addition bronchoscopy showed an eosinophil BAL and lipid bacuoles in the bronchial walls and in macrophages. It is postulated that the lipid came from the glue.

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An odd case report. Evidence for asthma not good, but work-relationship and steroid response clearer. Eosinophilic BAL, lipid laden macrophages in BAL, lipid droplets in alveolar walls, said to come from glue used in cardboard boxes, but no evidence for this. No challenge or PEF records

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