Oasys and occupational asthma banner logo

Stainless steel welding asthma shows active inflammation from differentially expressed genes, not seen with isocyanates or flour

Stainless steel welding asthma shows active inflammation from differentially expressed genes, not seen with isocyanates or flour
This is a complicated study investigating molecular mechanisms of work-related asthma due to flour, isocyanates and stainless steel welding. The welders were the only group showing active inflammation from differentially expressed genes in nasal mucosal biopsies, but asymptomatic welders were not included in the controls. All three groups showed activation of genes associated with neutrophil migration and degranulation. The numbers are rather small for generating associations from these three very different agents that can cause indistinguishable clinical disease.

References

Full Text Available for Endotyping asthma related to three different work exposures Suojalehto H, Ndika J, Lindström I, Airaksinen L, Karisola P, Alenius H, Endotyping asthma related to three different work exposures, J Allergy Clin Immunol, 2021;:,https://doi.org/10.1016/j.jaci.2021.07.019
Hille Suojalehto, Finnish Institute of Occupational Health, an author of 'Endotyping asthma related to three different work exposures' Irmeli Lindstrom, Finnish Institute of Occupational Health, an author of 'Endotyping asthma related to three different work exposures'

Comments

Please sign in or register to add your thoughts.


Oasys and occupational asthma smoke logo