Occupational asthma due to stainless steel welding; first large series

34 workers with specific challenge tests to stainless steel welding are described. Only 6 were able to continue welding with powered respiratory protection. Non specific reactivity was normal in 38% at presentation. All had negative skin prick tests to potassium dichromate 1mg/ml

Agent
Stainless steel welding fume

Jobs
Welders (24), machine fitters (4), Plumbers (3), metalworker (1), teacher (1), inspector (1)

Proof
Specific IgE not tested

Skin prick test to potassium dichromate 1mg/ml negative (0/24)

Non specific bronchial reactivity normal pre challenge 38%

Serial peak flow records positive 5/6 plus 3 proper evaluation not possible

Specific Bronchial Challenge: immediate reaction to welding fume (27%), late (47%) dual (27%)

Follow up
Only 6/34 continued welding with powered RPE; vocation rehabilitation(14); relocation away from exposure (4); early retirement (7)

References

	Hannu T, Piipari R, Tuppurainen M, Nordman H, Tuomi T, Occupational asthma caused by stainless steel welding fumes: a clinical study , Eur Respir J, 2007;29:85-90,

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