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 Home > Agents implicated in occupational asthma > Vancomycin

Vancomycin

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This table is from a case report of one patient. The authors suggest that the mechanism is direct histamine release.

Agent Vancomycin
Job Pharmaceutical manufacturer
Specific IgE negative
Skin prick test negative
Non-specific reactivity methacholine 0.933 mg/ml
Serial Peak Flow positive  (9.3-62% variablility on workdays, <10% on days off)
 BAL not done
 FENO not done
Basophil histamine release Significant histamine relase from patients basophils with 1ug/ml HSA conjugate, no release from controls. Authors  suggest mechanism is direct non-allergic histamine release
Specific Challenge 

Refused
Follow-up

no information



References for: Vancomycin See published papers on "Vancomycin" from this website.

Selected References for Vancomycin

Abstract Available for A case of occupational asthma caused by inhalation of vancomycin powder Choi G-S, Sung J-M, Lee J-W, Ye Y-M, Park H-S, A case of occupational asthma caused by inhalation of vancomycin powder, Allergy, 2009;64:1391-1392,
Hae-Sim Park, Korea, an author of 'A case of occupational asthma caused by inhalation of vancomycin powder'

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