Orthopaedic bone cement as a cause of occupational asthma

I've just seen a nurse who gives a real good history of asthma in relation to exposure to orthopaedic cement in theatres and a lesser reaction to wall paper paste at home! I can't find anything on Medline or in your book or in my references but I am sure this is something that has been described - can you advise me?

Occupational Asthma, Specialist, 11/15/2006, 11/15/2006,

We have 40 notifications of occupational asthma with acrylates as a possible cause on Shield since 1989. The most common jobs are assemblers (6), Gluers (4), Theatre nurse/healthcare worker/anaesthetic practitioner/operating dept assistant (5), Dentist/dental technicians/dental nurse (3). The Theatre Nurse had a positive challenge to bone cement (methylmethacrylate). There are a number of published papers as follows (those on cyanoacrylates have been omitted) Nayebzadeh A, Dufresne A, Evaluation of exposure to methyl methacrylate among dental laboratory technicians, Am Ind Hyg Assoc J, 1999;60:625-628, Weytjens K, Cartier A, Lemiere C, Malo JL, Occupational asthma to diacrylate, Allergy, 1999;54:289-290, Piirila P, Kanerva L, Keskinen H, Estlander T, Hytonen M, Tuppurainen M, Nordman H, Occupational respiratory hypersensitivity caused by preparations containing acrylates in dental personnel, Clin Exp Allergy, 1998;28:1404-1411, Spencer AB, Estill CF, McCammon JB, Mickelsen RL, Johnston OE, Control of ethyl methacrylate exposures during the application of artificial fingernails, Am Ind Hyg Assoc J, 1997;58:214-218, Wittczak T, Palczynski C, Szulc B, Gorski P, Bronchial asthma with inflammation of the nose mucous membrane induced by occupational exposure to methyl methacrylate in a dental technician, Medycyna Pracy, 1996;47:259-266, Raymond LW, Pulmonary abnormalities and serum immunoglobulins in facsimile machine repair technicians exposed to butyl methacrylate fume, Chest, 1996;109:1010-1018, Mizunuma K, Kawai T, Yasugi T, Horiguchi S, Takeda S, Miyashita K, Taniuchi T, Moon CS, Ikeda M, Biological monitoring and possible health effects in workers occupationally exposed to methyl methacrylate, Int Arch Occup Environ Health, 1993;65:227-232, Savonius B, Keskinen H, Tuppurainen M, Kanerva L, Occupational respiratory disease caused by acrylates, Clin Exp Allergy, 1993;23:416-424, Basker RM, Hunter AM, Highet AS, A severe asthmatic reaction to poly(methyl methacrylate) denture base resin, Brit Dental J, 1990;169:250-251, ReymaudGaubert M, PhilipJoet F, Arnaud A, Asthme professionnel au methyl-methacrylate, Presse Med, 1990;20:386-, Burgess KR, Thermal degredation products from an ethylene methacrylic acid copolymer-partial metal salt as the cause of industrial bronchitis, J Industr Med, 1987;29:752-753, Lozewicz S, Davison AG, Hopkirk A, Burge PS, Boldy DA, Riordan JF, McGivern DV, Platts BW, Davies D, Newman Taylor AJ, Occupational asthma due to methyl methacrylate and cyanoacrylates, Thorax, 1985;40:836-839, Thorpe LD, Valsecchi F, Sala C, Cesna MA, Evaluation of occupational risk and biological effects in a factory of polymethylmethacrylate sheets, Lav Um, 1982;30:72-79, Jedrychowski W, Styrene and methylmethacrylate in the industrial environment as a risk factor of chronic obstructive lung disease, Int Arch Occup Environ Health, 1982;51:151-157, Cohen SR, Maier AA, Flesch JP, Occupational health case report no 3: ethyl acrylate, J Occup Med, 1974;16:199-200,

11/15/2006